Eine lymphomähnliche Präsentation einer fokalen nodulären Hyperplasie (FNH) der Leber

Schmitz, Daniel; Köhler, H; Heußel, Claus-Peter; Löhr, H. F.; Galle, P

doi:10.1055/s-2001-11765

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…Changes of liver cirrhosis and ascites can also be seen with biliary dilatation (arrow in d ). MR images reveal a homogeneous, mildly T2-hyperintense, diffusion restricting lesion (asterisk in e and f ) Occasionally, a central “scar” can be seen in this type of hepatic lymphoma, mimicking focal nodular hyperplasia [ 33 ] (Fig. 5 ).…”

Section: Imaging Featuresmentioning

confidence: 99%

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The imaging conundrum of hepatic lymphoma revisited

et al. 2015

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The imaging manifestations of hepatic lymphoma, both in its primary and secondary form, are extremely variable and overlap with a number of other more common hepatic diseases. However, in the appropriate clinical context, combining the imaging and laboratory features can aid in making the correct diagnosis. Since the management and prognosis of lymphomas are significantly different from other malignancies, early diagnosis and prompt commencement of therapy is of paramount importance. The various morphological appearances of hepatic lymphoma on imaging have been described here along with their possible differentials.Teaching points• Primary hepatic lymphoma is extremely rare.• Secondary liver involvement occurs in 50 % of patients with non-Hodgkin lymphoma.• The imaging manifestations of hepatic lymphoma are largely non-specific.• Some imaging features may be helpful in the appropriate clinical setting.• Management and prognosis of lymphoma is significantly different from other malignancies.

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Section: Imaging Featuresmentioning

confidence: 99%

“…Occasionally, a central “scar” can be seen in this type of hepatic lymphoma, mimicking focal nodular hyperplasia [ 33 ] (Fig. 5 ).…”

Section: Imaging Featuresmentioning

confidence: 99%

The imaging conundrum of hepatic lymphoma revisited

et al. 2015

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Nodular lymphoid lesion of the liver with simultaneous focal nodular hyperplasia and hemangioma: discrimination from primary hepatic MALT-type non-Hodgkin’s lymphoma

et al. 2005

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Nodular lymphoid lesion (NLL) of the liver is a rare but unique entity and has also been termed reactive lymphoid hyperplasia of the liver. We describe the histological, immunohistochemical and molecular biologic findings of a case with NLL and two other tumors of the liver. The nodular lymphoid mass found in the liver was composed of heterogeneous small lymphocytes forming reactive follicles. Plasma cells, few immunoblasts, centroblasts, few macrophages, epithelioid cells, and giant cells were seen. The lymphoid infiltrate displaced the adjacent hepatic parenchyma. By immunohistochemistry and molecular studies, the lymphocytes were found to be polyclonal. The diagnosis of NLL was made. In addition to NLL, focal nodular hyperplasia and hemangioma were detected. The discrimination of NLL from primary hepatic malignant non-Hodgkin's lymphoma of mucosa-associated lymphoid tissue-type may pose diagnostic difficulties and may require the use of immunohistochemical and molecular techniques. The simultaneous occurrence of NLL with focal nodular hyperplasia and hemangioma in the liver has not been described before.

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Eine lymphomähnliche Präsentation einer fokalen nodulären Hyperplasie (FNH) der Leber

Abstract: The focal nodular hyperplasia can be a very difficult diagnosis in imaging and histopathological examinations. The lymphoma of the liver can be a rare but possible differential diagnosis.

Cited by 2 publications

References 8 publications

The imaging conundrum of hepatic lymphoma revisited

The imaging conundrum of hepatic lymphoma revisited

Nodular lymphoid lesion of the liver with simultaneous focal nodular hyperplasia and hemangioma: discrimination from primary hepatic MALT-type non-Hodgkin’s lymphoma

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