Ein neues Therapiekonzept bei Ästhesioneuroblastom

Walch, Christian; Stammberger, Heinz R.; Unger, F.; Anderhuber, W.

doi:10.1055/s-2000-9134

Cited by 15 publications

(11 citation statements)

References 14 publications

(20 reference statements)

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“…GKS was effective in the treatment of olfactory neuroblastomas [23,24]. This was not true in our case, possibly because the administered dose (marginal dose 15 Gy) was too small to control tumor growth.…”

Section: Discussioncontrasting

confidence: 71%

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Sellar Neuroblastoma Mimicking Pituitary Adenoma

et al. 2005

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Section: Discussioncontrasting

confidence: 71%

“…In our case, there was no evidence supporting neuronal transformation from pituitary epithelium. We postulate that its origin was the locus proposed by the latter investigators [23,24].…”

Section: Discussionmentioning

confidence: 94%

Sellar Neuroblastoma Mimicking Pituitary Adenoma

et al. 2005

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“…2–5,7–9) Stereotactic radiosurgery (SRS) may be effective for primary sellar neuroblastoma such as in previously reported cases with esthesioneuroblastoma. 14,15) SRS was actually effective in the present case, in spite of only a short follow-up period. Furthermore, some authors have recommended spinal radiation therapy in addition to conventional radiation therapy because patients with cerebral neuroblastoma, including sellar neuroblastoma, may exhibit metastatic spread within the spinal cord.…”

Section: Discussionmentioning

confidence: 43%

Primary Sellar Neuroblastoma in an Elderly Patient: Case Report

Yamamuro

Fukushima

Yoshino

et al. 2015

NMC Case Report Journal

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A 71-year-old male presented with an isolated well-enhanced sellar lesion accompanied by hypopituitarism, diagnosed preoperatively as a pituitary adenoma, meningioma, or metastatic brain tumor. However, histological examinations yielded a diagnosis of neuroblastoma. Primary sellar neuroblastoma in the elderly is very rare. We therefore describe this case of primary sellar neuroblastoma, mimicking common pituitary tumor, and review the literature. There have so far been only nine reported cases of primary sellar neuroblastoma in the English literature. All reports like the present case, demonstrated similar neuroimaging of a “dumbbell-shaped extension in the sellar region.” Moreover, the tumors may exhibit characteristic features, such as rapid tumor growth, hypopituitarism, or oculomotor nerve palsy, and these findings may represent helpful signs for the diagnosis of primary sellar neuroblastoma.

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“…At present, endoscopic techniques have been applied to the treatment of nasosinusal and skull base neoplasms. 7,10,[18][19][20] The indications and limitations of these techniques remain controversial, and need to be further defined, not only what may be done, but especially when.…”

Section: Discussionmentioning

confidence: 99%

Endoscopic treatment of esthesioneuroblastoma

Monteiro

Lopes

Santos

et al. 2011

Braz. j. otorhinolaryngol. (Impr.)

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Esthesioneuroblastoma is an uncommon malignant tumor of the nasal vault. Treatment consists of craniofacial resection. As endoscopic techniques have advanced, this approach has been recommended to avoid morbidity and to reduce costs. Aim To evaluate outcomes in patients with esthesioneuroblastoma treated by an endoscopic technique. Methods A prospective study of patients diagnosed with esthesioneuroblatoma and treated by an endoscopic technique. The literature over the past 20 years was reviewed for an update on the pathology. Results We present 4 patients, 3 males and 1 female, staged according to Kadish and Dulguerov. All were treated surgically with endoscopic techniques, followed by radiotherapy. One patient was also submitted to neck dissection and chemotherapy because of regional metastasis. There were no significant postoperative complications. The mean hospital stay was 3 days; one patient stayed in the ICU for 24 hours after surgery. Follow-up is recent; so far there are no recurrences. Conclusion Esthesioneuroblastoma is a potentially curable malignancy. Endoscopic techniques help reduce hospital costs and decrease the morbidity. Adequate margins of healthy tissue are obtained with endoscopic resection, as with craniofacial resection. The literature suggests that outcomes after endoscopic resection are similar to those of the conventional external approach.

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Ein neues Therapiekonzept bei Ästhesioneuroblastom

Abstract: Due to the excellent outcome of our six patients we recommend this new treatment concept, in selected cases, as an alternative to the usual therapeutic modalities for esthesioneuroblastoma.

Cited by 15 publications

References 14 publications

Sellar Neuroblastoma Mimicking Pituitary Adenoma

Sellar Neuroblastoma Mimicking Pituitary Adenoma

Primary Sellar Neuroblastoma in an Elderly Patient: Case Report

Endoscopic treatment of esthesioneuroblastoma

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