Eighteen-Point Abobotulinum Toxin A Upper Face Rejuvenation

Kashkouli, Mohsen Bahmani; Amani, Afsaneh; Jamshidian-Tehrani, Mansooreh; Yousefi, Sahar; Jazayeri, Anis Alsadat

doi:10.1097/iop.0000000000000053

Cited by 16 publications

(12 citation statements)

References 26 publications

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“…Complications associated with botulinum toxin injection at the upper face include blepharoptosis, persistence of eyebrow asymmetry post-touch-up, eyebrow ptosis, diplopia, dry eyes, and eyelid edema. 4 , 5 There is a rare and interesting phenomenon without adverse complications and discomfort. This phenomenon is thought to be related to the patient’s physiological structure.…”

Section: Discussionmentioning

confidence: 99%

Unilateral Double Eyelid Formation after Botulinum Toxin A Injection: A Case Report

Jiang

Liu

Wang

et al. 2022

Plastic and Reconstructive Surgery - Global Open

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Summary: Botulinum toxin injection has been widely used for facial rejuvenation, with high rates of efficacy and patient satisfaction. In this article, we describe a reproducible phenomenon of unilateral double eyelid formation with the treatment of upper facial rhytides using botulinum toxin. A 38-year-old man was given onabotulinum toxin A injections in the frontal stria and glabellar lines. The procedure was repeated after 6 months. Unilateral double eyelids were noted twice on the right side about 7 days after each injection. The maintenance time for each procedure was about 1 month. The rhytides improved about 3 days after each injection and were maintained for about 4 months. No adverse effects were observed. This rare phenomenon could be due to the compensatory increased strength of the levator palpebrae superioris muscle and the anatomical structure of the patient’s right eyelid.

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Section: Discussionmentioning

confidence: 99%

Unilateral Double Eyelid Formation after Botulinum Toxin A Injection: A Case Report

Jiang

Liu

Wang

et al. 2022

Plastic and Reconstructive Surgery - Global Open

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“…BTA may be used for eyebrow lifting by targeting both glabellar and crow's feet areas. [5] It mostly results in lateral eyebrow lift [ Figure 1]. Ahn et al [6] showed an average elevation in the central brow of 1 mm and of 4.8 mm in the lateral brow.…”

Section: Botulinum Toxin a (Bta) Injectionmentioning

confidence: 99%

“…The effect is temporary and lasts for three to six months. [5] Pain, asymmetries, bruising and ecchymosis, erythema and edema, headache, diplopia, focal facial paralysis, dry eye syndrome, blepharoptosis, exaggeration of wrinkles, and muscle weakness are some of the adverse effects that might be seen by BTA injection for the upper face. [5]…”

Section: Botulinum Toxin a (Bta) Injectionmentioning

confidence: 99%

Techniques of Eyebrow Lifting: A Narrative Review

Karimi¹,

Kashkouli²,

Sianati³

et al. 2020

JOVR

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None of brow lift techniques are completely satisfactory because of their limited effectiveness, lack of longevity, and potential complications. The aim of this study was to provide a comprehensive review of the literature on the pros and cons of the most popular techniques in brow and forehead lift. Relevant original articles in the PubMed database (English language) were sought using the search terms “eyebrow lift”, “forehead lift”, ”periorbital rejuvenation”, ”eyebrow ptosis”, ”blepharoplasty and eyebrow change”, ”surgical eyebrow lift”, and ”non-surgical eyebrow lift”, No date limitation was considered. Titles and abstracts were scanned to include the most pertinent articles. Subsequently, full texts of included articles (111 articles) were skimmed and finally 56 references were selected for the review. A narrative synthesis of data was finally undertaken with particular attention to the indications, techniques, and common complications of the eyebrow lift procedures. Ten popular techniques including two nonsurgical methods (Botulinum toxin A and soft tissue fillers) were reviewed in this article. In general, non-surgical methods of forehead/brow lift are temporary, need less experience and correction would be easier should any complication occur. Surgical methods are divided into three categories: trans-blepharoplasty eyebrow lift, direct eyebrow lift, and trans-forehead eyebrow/forehead lift. Currently, the most popular method is the endoscopic forehead lift approach even though its longevity is limited. Direct brow-lift is particularly useful in patients with facial palsy and those who are more likely to be accepting of the scar (male gender, high forehead hair line).

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“…Consequently, the use of BoNTA in cosmetics for the effacement of dynamic wrinkles is wide-spread (20). Aside from the removal of wrinkles, the use of BoNTA continues to increase in a number of applications for its face-lifting effects (21), anti-photoaging effects on the skin, scar reduction (22) and flap survival improvement (23). …”

Section: Introductionmentioning

confidence: 99%

Botulinum toxin A improves adipose tissue engraftment by promoting cell proliferation, adipogenesis and angiogenesis

Tang

Chen

Wang

et al. 2017

International Journal of Molecular Medicine

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Adipose tissue engraftment has become a well-established therapy in plastic and reconstructive surgery used to restore age-related or injury-related soft tissue loss. However, the unpredictable absorption rates limit its further application. Some clinicians have noted that more optimal aesthetic results are achieved when botulinum toxin A (BoNTA) is applied prior to adipose tissue grafting. In the present study, we transplanted allogeneic adipose tissue treated with or without BoNTA in SD rats in vivo. We subsequently evaluated the survival rate (weight, volume, apoptosis and cellular integrity) and revascularization of the adipose tissue. The results revealed that BoNTA improved the long-term weight and volume retention of the graft, and preserved cellular integrity. BoNTA significantly increased the expression levels of CD31 and vascular endothelial growth factor (VEGF), suggesting enhanced vasodilation and endothelial cell proliferation. In vitro, adipose-derived stem cells (ASCs) were isolated, identified and induced to proliferate and differentiate with or without BoNTA. Furthermore, to evaluate the proliferative, adipogenic and angiogenic ability of the ASCs, CCK-8 assay and Oil Red O staining were conducted. Gene and protein expression levels were analyzed by RT-qPCR and western blot analysis. The results revealed that 8×10−2 U/ml BoNTA as the optimal dose increased ASC proliferation and adipogenic differentiation capacity, as well as the expression level of the key cytokine of angiogenesis. On the whole, our findings indicate that BoNTA improves adipose tissue engraftment and promotes ASC regeneration, which could benefit future clinical applications.

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Eighteen-Point Abobotulinum Toxin A Upper Face Rejuvenation

Abstract: Eighteen-point ABO-BTA upper face rejuvenation had a low rate of AE in this series in which majority was bruise at the lateral canthal area. They were significantly more in the first years of experience, subjects younger than 40, and who had touch-up injections.

Cited by 16 publications

References 26 publications

Unilateral Double Eyelid Formation after Botulinum Toxin A Injection: A Case Report

Unilateral Double Eyelid Formation after Botulinum Toxin A Injection: A Case Report

Techniques of Eyebrow Lifting: A Narrative Review

Botulinum toxin A improves adipose tissue engraftment by promoting cell proliferation, adipogenesis and angiogenesis

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