2014
DOI: 10.1159/000357207
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Eight Years Later, Are We Still Hurting Newborn Infants?

Abstract: Objective: To study whether new pharmacological and nonpharmacological guidelines lowered numbers of painful procedures in neonates and changed the amount and frequency of analgesic therapy as compared to the results of our previous study in 2001. Design: A prospective observational study. Setting: Level III NICU of the Erasmus MC-Sophia Children's Hospital, Rotterdam. Participants: Neonates admitted at postnatal ages less than 3 days with length of stay at least 72 h. Main Outcome Measures: Number of all pote… Show more

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Cited by 178 publications
(154 citation statements)
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“…Epidemiological studies report that infants in the neonatal intensive care unit are subjected to an average of 11 painful procedures a day, not including the high numbers of failed attempts (up to 15; Carbajal et al 2008;Roofthooft et al 2014). These clinically required procedures can be incorporated into ethically approved investigative studies of CNS pain activity.…”
Section: Introductionmentioning
confidence: 99%
“…Epidemiological studies report that infants in the neonatal intensive care unit are subjected to an average of 11 painful procedures a day, not including the high numbers of failed attempts (up to 15; Carbajal et al 2008;Roofthooft et al 2014). These clinically required procedures can be incorporated into ethically approved investigative studies of CNS pain activity.…”
Section: Introductionmentioning
confidence: 99%
“…Moreover, admitted to the neonatal intensive care unit (NICU), they undergo many potentially painful procedures - estimated at 11 daily [2]. This may cause pain-related stress and alterations in the intracranial blood volume and blood pressure, with the risk of intraventricular hemorrhage and periventricular leukomalacia [3].…”
Section: Introductionmentioning
confidence: 99%
“…The assessment of pain should be performed to support clinical decisions regarding appropriate pain relief management and to attenuate the potential negative impact on the early and later development of the child (Hall & Anand, 2014;Roofthooft, Simons, Anand, & van Dijik, 2014). Pain management and comfort interventions increase the homeostasis and stability of preterm infants and help immature newborns cope with pain-related stress events in the NICU Johnston et al, 2014).…”
Section: Impact Of Pain On Developmentmentioning
confidence: 99%