Eight-Membered Rings With One Nitrogen Atom

Stereoselective two-carbon ring expansion of allylic amines via electronic control of palladium-promoted equilibria

“…1. 2,3 However, despite considerable effort being directed towards their synthesis, general routes to their construction have yet to be fully developed, thus limiting synthetic access to key chemical space. 4–6 Ring expansion processes offer an ideal approach to achieving this if they are capable of employing common-ring ( i.e.…”