Eicosanoids as Risk and Prognostic Factors for Acute Respiratory Distress Syndrome in Sepsis Patients

Takahashi, Goro; Shibata, Shigehiro; Endo, Shunsuke

doi:10.4172/2161-105x.1000435

Cited by 2 publications

(2 citation statements)

References 18 publications

(21 reference statements)

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“…Four survivors (4.9%) in the Ethanol Group were discharged to hospice care, comparable to 7 (3.1%) in the Control Group (p = 0.49). The need for home health services post-discharge was similar: 34.6% (28) in the Ethanol Group, and 28.9% (65) in the Control Group (p = 0.40). Considerably fewer patients required supplemental home oxygen in the Ethanol Group (45.7%; n = 37) versus the Control Group (64.4%; n = 82), though not statistically significant (p = 0.15).…”

Section: Resultsmentioning

confidence: 84%

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Nebulized Ethanol: An Old Treatment for a New Disease

Stogner¹

2023

Ethanol and Glycerol Chemistry - Production, Modelling, Applications, and Technological Aspects

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Ethyl alcohol (ethanol) is known to inactivate SARS-CoV-2, and therefore, direct delivery to the upper and lower respiratory tracts hypothetically would inhibit the progression of COVID-19. After informed consent, nebulized EtOH was given to inpatients admitted with COVID-19, and outcomes were retrospectively compared to randomly selected controls. Benefits of nebulized EtOH included decreased average length of stay, improved inpatient survival, decreased intubation rate and need for transfer to intensive care, improvement in hypoxemia, and decreased need for transfer to another facility for ongoing post-acute care. Also, fewer patients required supplemental home oxygen after discharge to home. Interpretation: Nebulized EtOH is beneficial in the treatment of COVID-19. Further study is warranted.

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Section: Resultsmentioning

confidence: 84%

“…Published reports suggest promise for the use of inhaled ethanol in the treatment of ARDS [28]. Ethanol is a well-known efficient surfactant (wetting agent), as it is an amphiphilic chemical compound possessing both hydrophilic and lipophilic properties.…”

Section: Nebulized Ethanol: Potential Benefits and Risksmentioning

confidence: 99%