Background
Sexually transmitted infections (STIs) including Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT) potentiate HIV acquisition and transmission especially among gay men and other men who have sex with men (MSM). We investigated the influence of sexual network composition on incident rectal GC and/or CT infections among Nigerian MSM.
Methods
TRUST/RV368 is a cohort of MSM recruited using respondent-driven sampling at trusted community centers in Abuja and Lagos, Nigeria. MSM respondents (egos) provided STI risk factors and demographic information for up to 5 of their most recent sexual partners (alters) within their sexual networks. Egos were tested for HIV, GC and CT every three months. Log-binomial regression was used to assess associations between alter characteristics and incident GC and/or CT.
Results
Between March 2013 and October 2015, 492 MSM were longitudinally screened for STIs, of which 28.0% (n = 138) were positive for incident rectal STI (61 GC only, 42 CT only, and 35 GC and CT). Among egos, condom use was associated with STIs [half of the time vs. never (adjusted risk ratio (aRR) 0.5; 95% CI 0.3– 0.8), always/almost always vs. never (aRR 0.7; 95% CI 0.5–1.0)]. Incident STIs were associated with having a younger alter ≤19 vs.30 years (aRR 0.6; 95% CI 0.4–1.0), HIV infection (aRR 1.5; 95% CI 1.1 –2.0) and engaging in sex under the influence of alcohol (aRR 1.4 95% CI 1.1–1.7) among regular alters and age, ≤19 vs.30 years (aRR 0.3; 95% CI 0.2–0.6), HIV infection (aRR 1.4; 95% CI 1.1 –1.8) and engaging in sex under the influence of alcohol (aRR 1.2 95% CI 1.0–1.4) among casual alters.
Conclusion
Given the centrality of sexual partner characteristics as risks for incident STIs among Nigerian MSM, there is a need to move beyond individual interventions and syndromic surveillance and get “out there” in the STI management.