“…15 This extraordinariness is determined by various aspects that directly concern the patient: (a) physical, (b) emotional (psychological), (c) axiological, and (d) economic. 16 The last aspect does not suggest that human life should be subject to economic calculations, but that costs related to the application of a therapy cannot be completely ignored (Hughes, 2020). Thus, regarding the physical aspect (a), the recognition of a therapy as persistent may involve pain that is difficult to eliminate or, more broadly, excessive suffering.…”