EFhd2 co-aggregates with monomeric and filamentous tau in vitro
Ahlam S. Soliman,
Andrew Umstead,
Jared Lamp
et al.
Abstract:Tauopathies are characterized by the abnormal buildup of tau protein, with early oligomeric forms associated with neurodegeneration and the later neurofibrillary tangles possibly conferring neuroprotection. The molecular mechanisms governing the formation of these tau species are unclear. Lately, there has been an increased focus on examining the interactions between tau and other proteins, along with their influence on the aggregation of tau. Our previous work revealed EFhd2’s association with pathological ta… Show more
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