Effusions Into Body Cavities in Hypothyroidism

Sachdev, Y; Hall, R.

doi:10.1016/s0140-6736(75)91571-8

Cited by 67 publications

(18 citation statements)

References 36 publications

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“…The mechanism by which effusions occur is part of a generalised polyseroupathy 5. The increased permeability of capillaries leads to extravasations of mucopolysaccharides accounting for exudative effusions.…”

Section: Discussionmentioning

confidence: 99%

Hypothyroidism presenting with recurrent pericardial tamponade

Arthur

Beeharry-Panray²,

Fitzgerald³

et al. 2009

Case Reports

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We present a case of pericardial tamponade caused by hypothyroidism. A 66-year-old man presented with acute chest pain radiating to the back. Computed tomography ruled out an aortic dissection but revealed a large pericardial effusion, which was confirmed on transthoracic echocardiography showing features of tamponade. The effusion was drained and subsequent thyroid function tests showed profound hypothyroidism. No other cause of the pericardial effusion could be identified. Despite the prompt initiation of levothyroxine (T4) replacement therapy, the effusion re-accumulated over a period of 10 days and required further drainage. Following that, aggressive thyroxine replacement therapy using liothyronine (T3) was initiated and there was no further re-accumulation. Hypothyroidism should be suspected in any cases of pericardial effusion where the cause is not obvious. We should be vigilant of re-accumulation, and T3 replacement therapy should be considered in that situation.

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Section: Discussionmentioning

confidence: 99%

Hypothyroidism presenting with recurrent pericardial tamponade

Arthur

Beeharry-Panray²,

Fitzgerald³

et al. 2009

Case Reports

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“…4) Pericardial effusion has been reported frequently in adults diagnosed with hypothyroidism. However, recent research suggests that early diagnosis of the disease precludes the occurrence of pericardial effusion.…”

Section: Discussionmentioning

confidence: 99%

Myxedema Associated with Cardiac Tamponade

et al. 2003

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SUMMARYPericardial effusion is frequently found in patients diagnosed with hypothyroidism, yet it is rarely associated with cardiac tamponade. This report presents an atypical case concerning a 60-year-old Taiwanese female, with a history of thyroidectomy surgery due to thyroid cancer, who was later diagnosed with myxedema and cardiac tamponade. Treatment included an immediate pericardiocentesis followed by thyroxine hormone replacement therapy. Postoperative and recovery phases progressed favorably, and the patient's prognosis is good. (Jpn Heart J 2003; 44: 447-450)

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“…Exudative serous effusions, especially within the pericardial, pleural and peritoneal cavities in association with primary hypothyroidism have long been recognized [11]. Although the exact mechanism by which these effusions develop remains unknown, an extravasation of hygroscopic mucopolysaccharides into the body cavities along with increased capillary permeability, decreased lymphatic drainage and increased salt and water retention have been proposed as possible causes [12][13][14].…”

Section: Laboratory Data On Admission After 8 Weeksmentioning

confidence: 99%

Panhypopituitarism Secondary to Rathkes Cleft Cyst Presenting With Pleuropericardial Effusions and Hypoalbuminemia

Imran¹,

Holness²,

Macaulay³

et al. 2003

The Endocrinologist

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Hypopituitarism is a relatively rare condition with a varying presentation, which depends upon the underlying etiology and the pattern of hormone insufficiency. A 42-year-old man with panhypopituitarism secondary to Rathkes cleft cyst, who sought treatment for pleural and pericardial effusions, is reported. Both effusions responded promptly to anterior pituitary hormone replacement therapy. (The Endocrinologist 2003;13: 91-94) From the *Division of Endocrinology and Metabolism, the †Division of Neurosurgery, and the ‡Department of Pathology, Dalhousie University, Halifax, Canada.

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Effusions Into Body Cavities in Hypothyroidism

Cited by 67 publications

References 36 publications

Hypothyroidism presenting with recurrent pericardial tamponade

Hypothyroidism presenting with recurrent pericardial tamponade

Myxedema Associated with Cardiac Tamponade

Panhypopituitarism Secondary to Rathkes Cleft Cyst Presenting With Pleuropericardial Effusions and Hypoalbuminemia

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