2019
DOI: 10.1080/14764172.2019.1660792
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Efficient treatment of upper-lip rhytidosis by pneumatic administration of hyaluronic acid

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Cited by 5 publications
(10 citation statements)
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“…A growing, but unregulated grey area, is the jet injection of hyaluronic acid for skin rejuvenation by non‐physicians. Other, more specialized indications are the delivery of bleomycin in common warts, anaesthetics for local pain management, botulinum toxin for hyperhidrosis, and 5‐aminolevulinic acid for photodynamic therapy 10–15 . Jet injectors can also be directed to target the subcutaneous tissue, for example, for administration of biologicals, vaccines, insulin, and nicotine 16–19 .…”
Section: Discussionmentioning
confidence: 99%
“…A growing, but unregulated grey area, is the jet injection of hyaluronic acid for skin rejuvenation by non‐physicians. Other, more specialized indications are the delivery of bleomycin in common warts, anaesthetics for local pain management, botulinum toxin for hyperhidrosis, and 5‐aminolevulinic acid for photodynamic therapy 10–15 . Jet injectors can also be directed to target the subcutaneous tissue, for example, for administration of biologicals, vaccines, insulin, and nicotine 16–19 .…”
Section: Discussionmentioning
confidence: 99%
“…The mechanical tension converts dermal fibroblasts into myofibroblasts by the induction of mechano‐responsive genes, accelerates fibroblast proliferation, and inhibits apoptosis 17 . It has been demonstrated that jet‐injected CL‐HA activates synthesis of new collagen type I and III up to 4 months after injection into the skin 10,18 with beneficial effects on facial wrinkles 10,19‐21 and acne scars 9,22 …”
Section: Discussionmentioning
confidence: 99%
“…The “true” clinical effect is determined by the generated tissue micro‐trauma and activated synthesis of ECM components. Although published data rarely report the treatment results beyond the 6‐month efficacy, 26,28,30,32,33 Levenberg 27 demonstrated improvement in Fitzpatrick‐Goldman wrinkle scale up to 18 months which was explained by continuous reorganization of the collagen during the final phase of the wound healing process.…”
Section: Longevity Of Effectmentioning
confidence: 99%
“…The triggered injury‐healing process promotes the neocollagenesis which is thought to gradually replace the initial HA hydration effect 25 . Progressive reduction of rhytidosis and improved turgor and elasticity 26‐28 can be observed as a new collagen continues to be accumulated for approximately 3‐6 months after the treatment 29 (Figure 5). Under higher injection pressure, HA micro‐droplets can be dispersed into deeper layers and generates a volume‐generated tension on fibro‐septal system (retinacula cutis) and superficial musculo‐aponeurotic system.…”
Section: Clinical Effectsmentioning
confidence: 99%
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