Efficient Synthesis of 2H-Indazolo[2,1-b]Phthalazine-Triones Using [PVPH]ClO₄ as a Modified Polymeric Catalyst

First Asymmetric Synthesis of Passerini‐Type Condensation Products in Water Using Pregabalin: A Chiral Amino Acid for the Efficient Asymmetric Induction

“…In continuation of our previous studies on the introduction of new catalysts for the promotion of multi‐component reactions [44–48] and specially bio‐organic ones, [49–51] in this investigation concurrent generation of carboxylic acids from the aerobic oxidation of aldehydes leading to α ‐acyloxycarboxamides with an stereogenic center and considerable ee by the supporting role of Pregabalin as an efficient reagent under the auxiliary of water is reported. It should be noted that although the role of amino acids in reaction with isocyanide and aldehydes was studied in the Ugi's reaction, [52–53] in this work we showed that by changing of the solvent and temperature the same reaction can lead to the production of the asymmetric Passerini's products (Scheme 3).…”

Comparison of the effectiveness of two piperazine based nano-catalysts in the synthesis of benzoxazoles and benzimidazoles and use of the powerful one in the N-Boc protection of amines

“…Aer extensive studies on the introduction and application of various catalysts in our research group, [45][46][47][48][49][50][51] and especially the use of nano-catalysts such as piperazine immobilized on nano-ZnO-sulfuric acid (PINZS) and piperazinium nano silica sulfonate (PNSS) in the synthesis of some organic compounds, 52,53 in this research we decided to compare the catalytic properties of PINZS and PNSS in the synthesis of benzimidazole and benzoxazole derivatives. This research shows the importance of choosing of the appropriate support in the immobilization of ionic liquids.…”

Sb(iii)/Gum Arabic composite as a new natural-based environmentally green catalyst for the one-pot pseudo-four-component synthesis of 2H-indazolo[2,1-b] phthalazinetriones

“…The above mentioned catalysts have high yields, [6][7][8]11 short reaction times, 7,10,11 easy work-up procedure, 7,10,11 solvent-free condition 6,11 and reusability of catalyst. 12 Some procedures have disadvantages such as strong acid condition 10 and no reusability catalyst. [8][9][10] Sb(III) is a good Lewis acid for activation of carbonyl compound.…”

“…The above mentioned catalysts have high yields, 6–8,11 short reaction times, 7,10,11 easy work-up procedure, 7,10,11 solvent-free condition 6,11 and reusability of catalyst. 12…”