Efficient Strategy to Synthesize Tunable pH-Responsive Hybrid Micelles Based on Iron Oxide and Gold Nanoparticles
Raúl Gimeno-Ferrero,
Javier Rodríguez de Jesús,
Manuel Pernia Leal
Abstract:The preparation of multifunctional nanomaterials based
on inorganic
nanoparticles with organic materials has emerged as a promising strategy
for the development of new nanomedicines for in vitro and in vivo
biomedical applications. Here, we synthesized pH-responsive hybrid
inorganic micelles by combining a novel pH-responsive amphiphilic
molecule with hydrophobic payloads. This amphiphile was synthesized
in a one-pot reaction and self-assembled readily into micelles under
acidic pH conditions. In the presence … Show more
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