Efficient stereoselective synthesis of aryl lactones using engineered ketoreductase ChKRED20 from Chryseobacterium sp. CA49
Mingliang Shi,
Rude Lin,
Yuan Yu
et al.
Abstract:Enzymatic asymmetric reduction of γ, δ-keto esters offer a convenient and efficient approach for producing optically active lactones. However, aryl lactones with bulky structures may not be readily prepared using...
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