Efficient solution methods for N-component condensation

Putten, Dennis S. van

doi:10.3990/1.9789036532655

Cited by 2 publications

(12 citation statements)

References 65 publications

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“…The variation of LPS epitope expression among the isogenic LPS variants at the single cell level was determined by immuno-electron microscopy using different LPS-specific monoclonal antibodies and gold-coupled conjugate, as described (Weel et al, 1989;van Putten et al, 1993). The samples were viewed with a Zeiss M 109 EM at 80 kV.…”

Section: Immuno-electron Microscopymentioning

confidence: 99%

Phase variation of lipopolysaccharide directs interconversion of invasive and immuno-resistant phenotypes of Neisseria gonorrhoeae.

1993

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Phase variation of Neisseria gonorrhoeae lipopolysaccharide (LPS) controls both bacterial entry into human mucosal cells, and bacterial susceptibility to killing by antibodies and complement. The basis for this function is a differential sialylation of the variable oligosaccharide moiety of the LPS. LPS variants that incorporate low amounts of sialic acid enter human mucosal epithelial cells very efficiently, but are susceptible to complement‐mediated killing. Phase transition to a highly sialylated LPS phenotype results in equally adhesive but entry deficient bacteria which, however, resist killing by antibodies and complement because of dysfunctional complement activation. Phase variation of N. gonorrhoeae LPS thus functions as an adaptive mechanism enabling bacterial translocation across the mucosal barrier, and, at a later stage of infection, escape from the host immune defence.

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Section: Immuno-electron Microscopymentioning

confidence: 99%

Phase variation of lipopolysaccharide directs interconversion of invasive and immuno-resistant phenotypes of Neisseria gonorrhoeae.

1993

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“…It is not easy to determine whether one component is dominant in saturation or not. In fact, two components with very different partial vapor pressures and very different saturation vapor pressures can have similar saturations (also called 'activities' in some literature [5] in case a mixture of species is concerned). Therefore, a general classical multispecies nucleation theory is formulated here.…”

Section: Nucleation Of Aerosolmentioning

confidence: 99%

“…The method will be illustrated for spatially homogeneous systems, for which a tailored adaptive time-stepping method is put forward to handle the very rapid nucleation burst, followed by the much slower evolution due to condensation and coalescence. We validate the new formulation by comparing full solutions of a ternary system of alcohol vapors based on the numerical solution to the BD equations [5]. The capability of the new approach is illustrated by studying aerosols from alcohol vapors containing up to five different species, for which the size distribution of the aerosol droplets as well as the chemical composition is computed under different initial temperatures and cooling rates at constant pressure drop.…”

Section: Introductionmentioning

confidence: 99%

“…A recent study based on Becker-Döring theory was presented in [5], considering the mixtures of alcohols in particular. A specialized multigrid solver was developed in order to efficiently solve the composition of droplets in n-component mixtures.…”

Section: Introductionmentioning

confidence: 99%

“…The element of simultaneous laminar fluid flow will be integrated in later studies and is a subject of ongoing research. To allow at this stage a cross-validation with fully resolved Becker-Döring theory [5], the method is illustrated for a system of alcohol vapors. Effects of (a) the temperature levels, (b) the cooling rate, and (c) the mixture composition will be investigated, and the consequences for the droplet composition and sizes are determined using the new model.…”

Section: Introductionmentioning

confidence: 99%

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Simulation of aerosol formation due to rapid cooling of multispecies vapors

et al. 2017

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Efficient solution methods for N-component condensation

Cited by 2 publications

References 65 publications

Phase variation of lipopolysaccharide directs interconversion of invasive and immuno-resistant phenotypes of Neisseria gonorrhoeae.

Phase variation of lipopolysaccharide directs interconversion of invasive and immuno-resistant phenotypes of Neisseria gonorrhoeae.

Simulation of aerosol formation due to rapid cooling of multispecies vapors

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