Abstract:Chromatographic separation processes need efficient simulation methods, especially for nonlinear adsorption isotherms such as the Langmuir isotherms which imply the formation of concentration shocks. The focus of this paper is on the space–time conservation element/solution element (CE/SE) method. This is an explicit method for the solution of systems of partial differential equations. Numerical stability of this method is guaranteed when the Courant–Friedrichs–Lewy condition is satisfied. To investigate the a… Show more
“…24). 236 Clearly, this feature makes this technique particularly appealing for the purification of binary mixtures such as racemates. This chromatographic mode allows one to increase the stationary phase utilization and therefore achieves a much higher throughput than the batch and, furthermore, can save up to 90% of the mobile phase, which is a great result from the point of view of green chemistry, especially at commercial scale.…”
Developing greener synthetic processes is an inescapable necessity to transform the industrial landscape, mainly in the pharmaceutical sector, into a long-term, sustainable reality. In this context, the renaissance of peptides...
“…24). 236 Clearly, this feature makes this technique particularly appealing for the purification of binary mixtures such as racemates. This chromatographic mode allows one to increase the stationary phase utilization and therefore achieves a much higher throughput than the batch and, furthermore, can save up to 90% of the mobile phase, which is a great result from the point of view of green chemistry, especially at commercial scale.…”
Developing greener synthetic processes is an inescapable necessity to transform the industrial landscape, mainly in the pharmaceutical sector, into a long-term, sustainable reality. In this context, the renaissance of peptides...
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