Efficient ruthenium-catalyzed hydrogenation of aromatic dicarboxylates supported by a 1-phenylethylamine-based P,N,N-ligand

C–H activation-initiated spiroannulation reactions and their applications in the synthesis of spirocyclic compounds

“…In this regard, Wang's group developed the synthesis of spiro[isobenzofuran-1,4′-isoquino- line]-3,3′-diones via CHA-initiated spiroannulation of 4-diazoisoquinolin-3-ones with benzoic acids, which usually only have weak coordinating capability (Scheme 27). 22 In addition to the carboxyl group, the carbonyl group in enaminones could also serve as an effective DG. In this context, we developed a synthesis of homophthalimide spironaphthalenones from the cascade reactions of enaminones with diazo homophthalimides.…”