Efficient production of l‐glutathione by whole‐cell catalysis with ATP regeneration from adenosine
Siqi Zuo,
Jiarun Zhao,
Pengfei Zhang
et al.
Abstract:Abstractl‐glutathione (GSH) is an important tripeptide compound with extensive applications in medicine, food additives, and cosmetics industries. In this work, an innovative whole‐cell catalytic strategy was developed to enhance GSH production by combining metabolic engineering of GSH biosynthetic pathways with an adenosine‐based adenosine triphosphate (ATP) regeneration system in Escherichia coli. Concretely, to enhance GSH production in E. coli, several genes associated with GSH and
l‐cysteine degradation,… Show more
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