Efficient preparation of 9-aryl-1,8-dioxo-octahydroxanthenes catalyzed by nano-TiO₂with high recyclability

Abstract

9-Aryl-1,8-dioxo-octahydroxanthene derivatives are synthesized by the reaction of arylaldehydes with dimedone (5,5-dimethyl-1,3-cyclohexanedione) in the presence of nano-TiO 2 as an efficient and heterogeneous catalyst under solvent-free conditions. Simple methodology, easy workup procedure, clean reaction, short reaction time, reusability of the catalyst up to 12 times and high yields are some advantages of this work.

Design and synthesis of a new porous organic polymer equipped with N‐propyl sulfamic acid functionalities: As an efficient heterogeneous catalyst for the synthesis of 1,8‐dioxo‐octahydroxanthene derivatives

“…A comparative study has been performed to demonstrate the merit of the present synthesized catalyst 4 in comparison with the previously reported methods (Table ) . As seen, this work presents a considerably efficient catalyst for being applied in 1,8‐dioxo‐octahydroxanthene derivatives synthesis in terms of the obtained products’ yields and also the reaction times and conditions…”

Design and characterization of nano-silica-bonded 3-n-propyl-1-sulfonic acid imidazolium chloride {nano-SB-[PSIM]Cl} as a novel, heterogeneous and reusable catalyst for the condensation of arylaldehydes with β-naphthol and alkyl carbamates

“…Nanocatalysts continue to attract attention for a variety of research disciplines because of their different chemical and physical characteristics once compared with bulk materials. The nano-sized particles maximize the surface area exposed to the reagents facilitating more reactions to take place concurrently, which, therefore, enhances the rate of the chemical reaction [22][23][24][25][26][27].…”

Preparation and characterization of Cu (II) supported on poly(8‐hydroxyquinoline‐p‐styrene sulphonate) and its application as catalyst for the synthesis of hexahydroquinolines

“…This part of quinoline derivatives has very usages in medicinal chemistry, being used as antiasthamatic, antibacterial antihypertensive, anti‐inflammatory, antimalarial, and tyrosine kinase inhibiting compounds . One of the categories of dihydropyridines (DHPs) with a modified structural scaffold is hexahydroquinolines (HHQs) which could be obtained through Hantzsch synthesis by the one‐pot four‐component condencation reaction of various aromatic aldehydes with dimedone, β ‐ketoesters and ammonium acetate in the presence of various catalysts such as silica‐bonded imidazolium‐sulfonic acid chloride, nano‐Fe 3 O 4 , 1,3‐disulfonic acid imidazolium hydrogen sulfate, nano‐Mn‐[4‐nitrophenyl‐salicylaldimine‐methyl pyranopyrazole]Cl 2 …”