Efficient ligand-free Hiyama cross-coupling reaction catalyzed by functionalized SBA-15-supported Pd nanoparticles

Abstract

Functionalized SBA-15-supported Pd catalysts were prepared as efficient and recyclable catalysts for ligand-free Hiyama cross-coupling under relatively mild reaction conditions.

Development of a Sulfur-Modified Glass-Supported Pd Nanoparticle Catalyst for Suzuki–Miyaura Coupling

“…For example, it has recently reported that traditional palladiumcatalyzed reactions that require a zero valent/divalent palladium catalyst and a suitable ligand (i.e., phosphine ligands and nitrogen-containing heterocyclic carbenes), can progress under ligand-free conditions using PdNPs. [3][4][5][6][7][8] There are therefore numerous advantages associated with the use of PdNP catalysts, including reduced processing costs, shorter reaction times and cleaner reaction profiles, which can have a positive impact on product purification. Based on their many attractive qualities, it is envisaged that PdNPs will become increasingly important for the synthesis of pharmaceutical agents and functional materials.…”

Applications of SBA-15 supported Pd metal catalysts as nanoreactors in C–C coupling reactions

“…Subsequently, Pd NPs preferentially incorporate to the latter using a solution of PdCl 2 (MeCN) 2 following reduced by hydrogen ow at 573 K to form Pd@M-SBA-15 (70) catalyst. 147 The nanocomposite catalysts exhibited excellent activity for the cross-coupling of various aryl halides with aryltriethoxysilanes in the mixture of tetra-n-butylammonium uoride trihydrate (TBAF$3H 2 O) under moderately mild reaction conditions to form different biphenyl derivatives in good to excellent yields (Scheme 117). Moreover, the catalysts could be recycled, and the decreased catalytic activity was ascribed to a little level of Pd-leaching and slow collapse of mesoporous of host silica aer sequential catalytic runs.…”

The Hiyama Cross‐Coupling Reaction: New Discoveries

“…Palladium nanoparticles supported on SBA‐15, a mesoporous silica, was successfully used for the cross‐coupling of aryl chlorides or bromides 5 with phenyltriethoxysilane 9 in the presence of TBAF yielding the expected biaryls derivatives 8 with variable results (Scheme ) 9…”