Efficient induction of cytotoxic T lymphocytes specific to hepatocellular carcinoma using HLA-A2-restricted MAGE-n peptide in vitro

Dong, Hailong; Sui, Yan-Fang; Li, Zengshan; Qü, Ping; Wu, Wen‐Hsiung; Ye, Jing; Zhang, Xiumin; Lu, Shao-Ying

doi:10.1016/j.canlet.2004.02.013

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Cited by 5 publications

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“…+ as previously reported (20)(21)(22). Our results showed the MAGE-n gene was expressed in KATO-III and HHCC+MAGE-3 cells.…”

Section: Cytotoxic Activity Of the Induced Ctl Cells Hhcc Kato-iii supporting

confidence: 54%

“…T2 cells, which bear the HLA-A*0201 gene, but express a very low level of cell surface HLA-A2.1 molecules and are unable to present endogenous antigens due to a deletion of most of the MHC class II region including TAP (transporter-associated with antigen processing) and proteosome genes, were kindly provided by Dr Sun Zongtang (Chinese Academy of Medical Sciences). Hepatocellular carcinoma cell lines HHCC, gastric carcinoma cell lines KATO-III and breast carcinoma cell lines MCF-7 were all HLA-A2 + and cultured in our lab (20)(21)(22)(23). All these cell lines were maintained in RPMI-1640 medium (Invitrogen, USA) supplemented with 12% fetal bovine serum (FBS, Hyclone, USA) and antibiotics.…”

Section: Methodsmentioning

confidence: 99%

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