Efficient incorporation and protection of lansoprazole in cyclodextrin metal-organic frameworks

Abstract

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Cyclodextrin metal–organic frameworks and derivatives: recent developments and applications

“…It has been demonstrated that CD-MOFs can also be used to store and stabilize non-gaseous unstable chemical compounds. 163,164,204 For example, Wang et al synthesized a β-CD-MOF for enhancing the stability of Anise leaf polyphenols (ALPs). 204 Generally, phenolic compounds extracted from plants are highly unstable and rapidly transform into various reaction products during food and drug processing, which limits their applicability.…”

Solid-State NMR Spectroscopy: A Key Tool to Unravel the Supramolecular Structure of Drug Delivery Systems

“…This indicates that the CF 3 group is in close contact to the CH 2 OH; hence, it is located outside the CD. In combination with DFT simulation, the data indicated the formation of a 2:1 γ-CD:lansoprazole complex [ 36 ].…”

Supramolecular Association between γ-Cyclodextrin and Preyssler-Type Polyoxotungstate

“…These oligosaccharides made of 6 (α), 7 (β) or 8 (γ) glucopyranose units exhibit a hydrophobic internal cavity capable of hosting a large variety of inorganic compounds of appropriate size and shape [11]. These macrocyclic cavitands have found utility in various fields of application such as catalysis [12], materials science [13], sensing [14], and drug delivery [15]. Driven by the chaotropic effect, CDs can remarkably encapsulate either cationic [16], anionic [17][18][19][20] or even neutral metallic species [21].…”