Efficient N-formylation of primary aromatic amines using novel solid acid magnetic nanocatalyst

Abstract

Sulfonic acid functionalized over biguanidine fabricated silica-coated heterogeneous magnetic nanoparticles (NP@SO3H) have been synthesized, well characterized and explored for the first time, as an efficient and recyclable catalyst for N-formylation of primary amines under mild reaction conditions.

Metal-Free N-Formylation of Amines Using Carbohydrates as C1 Synthon via C–C Bond Cleavage

“…This is a known compound, and the compound is a mixture of rotamers and the data for the major rotamer are given. 90 The crude product was purified by column chromatography on silica gel (EtOAc/hexane 2: 8) to give 3u as a light-brown colored solid; yield: 126 mg (92%). This is a known compound, and the compound is a mixture of rotamers and the data for the major rotamer are given.…”

New N‐phenylacetamide‐linked 1,2,3‐triazole‐tethered coumarin conjugates: Synthesis, bioevaluation, and molecular docking study

“…Diversely functionalized 1,2,3‐triazole derivatives have attracted great attention due to their extensive biological properties such as antioxidant, [ 5 ] antifungal, [ 6,7 ] antitubercular, [ 8 ] antibacterial, [ 9 ] anticancer, [ 10 ] anti‐HIV, [ 11 ] antimicrobial, [ 12 ] and antimalarial activity. [ 13 ] The 1,4‐disubstituted‐1,2,3‐triazoles were synthesized via copper‐catalyzed azide–alkyne cycloaddition reaction, well known as a click chemistry reaction.…”