Efficient energy localization for hybrid wideband hyperthermia treatment system

Abstract

This article presents efficient energy localization approach for hybrid wideband system for hyperthermia treatment of cancer based on a transmission line (TL). A heterogeneous head phantom is built by incorporating frequency dependent tissue properties of head layers considering both electromagnetic and ultrasound treatment. Effective medium properties are derived and used to compensate signal phase and magnitude values based on TL model. The obtained field map results emphasize the feasibility of the developed approach to obtain system parameters that enhance energy localization and eradicate hotspots.

SAR optimization for multi-dipole antenna array with regard to local hyperthermia

“…or in the opposite form containing the frequency bandwidth of interest [12]. In current case a volume marked by term target represents the small sphere and term all targets was equivalent for both spheres.…”

“…By utilizing several EMF sources with the appropriate power, amplitude and phase control of the power supply signals, the required heat focusing within the deep-seated tumors can be achieved [10,11]. For better targeting the EM energy on treated tissue the hybrid wideband multichannel HT systems [12] may be used. Furthermore, the multi-frequency field focusing devices can be applied to limit the so-called hot spots [13].…”

“…Furthermore, the multi-frequency field focusing devices can be applied to limit the so-called hot spots [13]. To prevent superficial tissues overheating, the appropriate frequency and number of applicators can be employed [12]. According to bioheat equation, the requested temperature levels of given tissue are connected with corresponding specific absorption rate (SAR) values [14].…”

Microwave Hyperthermia Application with Bioimplant Single Slot Coaxial Antenna Design for Mouse Breast Cancer Treatment

“…In most of the studies such as [20][21][22], important design parameters, such as the electrical characterization of the radiating antenna, reflection coefficient graphics, farfield radiation, SAR values on the tissue and other primary details that concern the engineers who will make the design, are not given sufficiently. In many studies showing details about the engineering aspects, publications are mostly limited to theoretical or simulation, antenna fabrication or measurements for application are not given [23][24][25][26][27] or the proposed designs are costly, far from being compact or production techniques of them are not suitable for mass production [25,26,[28][29][30]. In this study, different from the others, all details concerning electrical and electronic engineering, such as theoretical background, simulation, fabrication, and measurements related to the microwave heating and hyperthermia are presented.…”

Coherent energy projection of modulated signals from a sparse array

“…Moreover, coherently combining waveforms in this way actually scales via a square of the number of platforms, rather than just being additive. There is a need to project electromagnetic energy by using sparse arrays in applications ranging from electromagnetic hyperthermia treatment to precision electronic warfare . It is suggested in Reference that coherently combining large numbers of signals can be immensely powerful, yielding significant increases in communication and detection range in challenging RF (radio frequency) environments.…”