Nd:Lu 3 ScAl 4 O 12 single crystal has been grown by the Czochralski method. The segregation coefficient of Nd 3+ ions in LuSAG crystal is 0.22. X-ray powder diffraction (XRD) experiments show that the Nd:LuSAG crystal crystallizes in cubic structure with space group Ia3d and its cell parameters are a = 1.1953 nm. The absorption and fluorescence spectra of Nd:LuSAG crystal were investigated at room temperature. The spectral parameters were calculated based on Judd-Ofelt (J-O) theory, and the intensity parameters 2 , 4 and 6 were obtained to be 0.14, 3.38, and 4.88 × 10 −20 cm 2 , respectively. The calculated spontaneous radiative probabilities, branching ratios, radiative lifetime and quantum efficiency have been evaluated for the 4 F 3/2 excited state using the calculated intensity parameters. The results indicate that this crystal can be considered as a promising material for solid-state laser application.