Efficient designs for three-sequence stepped wedge trials with continuous recruitment
Richard Hooper,
Olivier Quintin,
Jessica Kasza
Abstract:Background/Aims: The standard approach to designing stepped wedge trials that recruit participants in a continuous stream is to divide time into periods of equal length. But the choice of design in such cases is infinitely more flexible: each cluster could cross from the control to the intervention at any point on the continuous time-scale. We consider the case of a stepped wedge design with clusters randomised to just three sequences (designs with small numbers of sequences may be preferred for their simplici… Show more
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