Efficient calculation of continuous trajectory spherical center displacements by using non-contact R-test

Abstract

Non-contact R-test is used for the dynamic measurement of five-axis machine tools. However, due to the spherical curvature, calculating the spherical center displacement (SCD) by using the non-contact R-test is challenging and inefficient. Thus, in this paper, an efficient calculation method based on multiple Gaussian process regression (GPR) is proposed to calculate the SCDs of the continuous trajectory by using the non-contact R-test. In the proposed method, first, the transformation matrix is constructed to roughly calculate the SCD. Second, the measurement error caused by the spherical curvature is solved and compensated by using the GPR model. Next, the threshold is set to remove some of the set points and reconstruct GPR to improve the model accuracy. Finally, the transformation matrix and the GPR model are outputted to calculate the SCDs of the continuous trajectory. We constructed a micro S trajectory to verify the proposed method. Experimental results showed that compared with the neural network method, the proposed method achieves higher model accuracy with shorter model construction time and improves the calculation efficiency by 99%.

Comprehensive Review on the Synthetic Strategies toward Anti-SARS-CoV-2 Drug Ensitrelvir

“…Subsequently, cyclization was performed using a highly efficient reagent isocyanatocarbonyl chloride with a yield of 86.8% on a 5.5 g scale . From intermediate 31 to final target ensitrelvir, N 3 -alkylation and substitution were performed under the common conditions in 58.1% and 77.1% yields on a 4 g scale, respectively. , During the synthesis of material 32 , when three reagents involving material 53 , DBU, and CDI participated, the triazinone moiety was constructed in different solvents in 54.0–65.0% yield on a 1 mmol scale …”

“…When the reaction temperature was controlled at the high boiling point using the combination of AcOH and (CH 3 ) 3 OH, the yield was significantly increased to 77.1% . Using butan-1-ol or HCOOH, the yield was 67.0% and 71.8%, respectively. When butyric acid was used as the solvent at the temperature of up to 150 °C, the yield was obviously increased to 84.5% .…”

“…Starting from trifluorobenzyl derivatives 3a and 3c (Figure ), the same isothiocyanate compound 63 was obtained by different methods using KSCN or TDCI/CS 2 (CSCl 2 ), but the yields were not reported. , Because 3c was commonly from 3a and the greener reagents, the strategy from 3a might be a good choice. Then the thiourea compound 64 was prepared in the presence of ammonia gas.…”

“…Then the thiourea compound 64 was prepared in the presence of ammonia gas. Subsequently, the preparation of compound 65 was performed under the conditions of iodoethane in alcohol at 30–120 °C with the yield reaching of 88.0% . Noteworthy, the other method of preparing compound 65 was performed under the condition of iodoethane in methanol at room temperature with the yield of 56.4%…”