Efficient biosynthesis of CuO nanoparticles with potential cytotoxic activity

Mahmoud, Nesrine M.R.; Mohamed, Hadeer; Ahmed, Somia B.; Akhtar, Sultan

doi:10.1007/s11696-020-01120-6

Cited by 25 publications

(7 citation statements)

References 53 publications

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“…Peaks recorded at 32.65°, 35.01°, 38.50°, 48.60°, 53.62°, 58.72°, and 60.71° corresponded to the miller indices (hkl) values at (110), (002), (111), (202), (020), and (113), respectively. These peaks are well matched with JCPDS card number 45-0937 ( Mahmoud et al, 2020 ). The average crystallite size of CuO-NPs crystals obtained with Debye Sherrer equation was found to be 14 nm.…”

Section: Resultssupporting

confidence: 72%

Photocatalysis and adsorption kinetics of azo dyes by nanoparticles of nickel oxide and copper oxide and their nanocomposite in an aqueous medium

Ahsan

Shahid

Imran

et al. 2022

PeerJ

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Background Azo dyes are recalcitrant organic pollutants present in textile industry effluents. Conventional treatment methods to remove them come with a range of disadvantages. Nanoparticles and their nanocomposites offer more efficient, less expensive and easy to handle wastewater treatment alternative. Methods In this study, nanoparticles of nickel oxide (NiO-NPs), copper oxide (CuO-NPs) and their nanocomposite (NiO/CuO-NC) were synthesized using co-precipitation method. The functional groups present on the surface of synthesized nanomaterials were verified using Fourier-transform infrared spectroscopy (FTIR). Surface morphology was assessed using scanning electron microscopy (SEM) whereas purity, shape and size of the crystallite were determined using X-ray diffraction (XRD) technique. The potential of these nanomaterials to degrade three dyes i.e., Reactive Red-2 (RR-2), Reactive Black-5 (RB-5) and Orange II sodium salt (OII) azo dyes, was determined in an aqueous medium under visible light (photocatalysis). The photodegradation effectiveness of all nanomaterials was evaluated under different factors like nanomaterial dose (0.02–0.1 g 10 mL−1), concentration of dyes (20–100 mg L−1), and irradiation time (60–120 min). They were also assessed for their potential to adsorb RR-2 and OII dyes. Results Results revealed that at optimum concentration (60 mgL−1) of RR-2, RB-5, and OII dyes, NiO-NPs degraded 90, 82 and 83%, CuO-NPs degraded 49, 34, and 44%, whereas the nanocomposite NiO/CuO-NC degraded 92, 93, and 96% of the said dyes respectively. The nanomaterials were categorized as the efficient degraders of the dyes in the order: NiO/CuO-NC > NiO-NPs > CuO-NPs. The highest degradation potential shown by the nanocomposite was attributed to its large surface area, small particles size, and quick reactions which were proved by advance analytical techniques. The equilibrium and kinetic adsorption of RR-2 and OII on NiO-NPs, CuO-NPs, and NiO/CuO-NC were well explained with Langmuir and Pseudo second order model, respectively (R2 ≥ 0.96). The maximum RR-2 adsorption (103 mg/g) was obtained with NiO/CuO-NC. It is concluded that nanocomposites are more efficient and promising for the dyes degradation from industrial wastewater as compared with dyes adsorption onto individual NPs. Thus, the nanocomposite NiO/CuO-NC can be an excellent candidate for photodegradation as well as the adsorption of the dyes in aqueous media.

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Section: Resultssupporting

confidence: 72%

Photocatalysis and adsorption kinetics of azo dyes by nanoparticles of nickel oxide and copper oxide and their nanocomposite in an aqueous medium

Ahsan

Shahid

Imran

et al. 2022

PeerJ

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“…64 In comparison with that of other chemically formed CuO-NPs, it was obviously disclosed that the IC 50 of prepared CuO-NPs was 65 μg/mL for the normal cell. 65 These findings emphasize that the chemically prepared CuO-NPs reached IC 50 for normal cells at an earlier low concentration comparing with biologically prepared ones. Therefore, the biosynthesized CuO-NPs exhibited lower cytotoxicity than other methods.…”

Section: Methodsmentioning

confidence: 63%

“…aqueous extract on the viability of human normal cells at concentrations up to 100 μg/mL . In comparison with that of other chemically formed CuO-NPs, it was obviously disclosed that the IC 50 of prepared CuO-NPs was 65 μg/mL for the normal cell …”

Section: Resultsmentioning

confidence: 94%

Integration of Cotton Fabrics with Biosynthesized CuO Nanoparticles for Bactericidal Activity in the Terms of Their Cytotoxicity Assessment

Shaheen

Fouda

Salem

2021

Ind. Eng. Chem. Res.

125

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Green biosynthesis of highly active materials for healthcare and hygiene products, such as medical textiles that allow us to wear comfortable clothes with potent protection elements, is in great demand nowadays, as our surroundings have become infected with dangerous microbes. Herein, CuO nanoparticles were biosynthesized successfully by exploiting the active enzymes/proteins secreted by fungi, with consideration of their cytotoxicity, for the production of antibacterial active textiles. The fungus, namely, Aspergillus terreus strain AF-1, was allowed to secrete active ingredients including enzymes and the protein needed to cap the formed CuO-NPs. Characterizations of the CuO-NPs were performed in order to assign the chemical and physical properties of the nanoparticles yielded using Fourier transform infrared (FT-IR), X-ray diffraction (XRD), Raman spectra, transmission electron spectroscopy (TEM), and energy dispersive X-ray and X-ray photoelectron (XPS) spectroscopies. Cotton fabrics were treated with CuO-NPs prior to experiment to investigate the cytotoxicity of CuO-NPs to estimate the safe dose of nanoparticles. At the CuO-NPs safe dose, the treatment of cotton fabrics was performed, and their antibacterial activities were examined through a comparison of the fabrics before and after CuO-NPs treatment. Our findings affirmed the role of fungus secreted protein for capping CuO in spherical CuO-NPs during formation with sizes in the range of 11–47 nm as determined by TEM. New functional particles attached on the cotton surface were affirmed by FT-IR, while the crystallographic structure of the formed CuO-NPs was also confirmed by XRD. XPS depicted clearly the biosynthesize of CuO-NPs, and these results were concordant with FT-IR and XRD results. As per the cytotoxicity results, fabrics were treated with CuO-NPs at a safe dose (100 μg/mL) and, in turn, advocated plausible antibacterial efficacy versus pathogenic bacteria.

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“…Overlapping between N -H, -OH starching from chitosan [32][33]with -OH of carboxylic acid, phenol or alcohol and C -H starching vibration of aliphatic compound of pomegranate peel [34] 1626 Carbonyl group of amides [33] 1521 N -H bending vibration of amide [32] 1371 -CH 3 Symmetricaldeformation mode of amide group [32] 1327 Skeletal vibration of aromatic ring of pomegranatepeel [34] 1094 Skeletal starching vibration of C -O [32][33] [34] from both chitosan and pomegranate peel 618 Interaction between chitosan and Cu-NP's [33] The data listed in table (1) illustrates that the difference in the FT-IR pattern between Cs-NP's and Cs-CuO-NP's is due to the existence of a few peaks belonging to Cs-CuO-NP's at 1327 cm -1 which indicate the existence of skeletal vibration of aromatic ring of pomegranate peel; this is besides peaks at 3550-2902 and 1094 cm -1 , which overlap with the peaks of chitosan. On the other hand, the appearance of a peak at 616 cm -1 and the shifting in many of the peaks' location clearly refers to the interaction between nano chitosan and CuO [32][33][34] [35].…”

Section: -2902mentioning

confidence: 99%

Investigation of the Antimicrobial Activity and Hematological Pattern of Nano-Chitosan and its Developed Nano-Copper Composite

Ahmed

Mohamed

Al‐Subaie

et al. 2021

Preprint

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Novel synthesized Chitosan-Copper oxide nanocomposite (Cs-CuO) was prepared using pomegranate peels extract as green precipitating agents to improve the biological activity of Cs-NP's which was synthesized through ionic gelation method. The characterization of biogenic nanoparticles Cs-NP's and Cs-CuO-NP's were investigated structurally, morphologically to determine the full descriptive features of those nanoparticles. Antimicrobial activity was tested for both Cs-NP's and Cs-CuO-NP's via Minimum inhibition concentration and zone analysis against fungus, gram positive and gram negative. The results of the antimicrobial test showed high sensitivity of Cs-CuO-NP's to all microorganisms that are tested in concentration less than 20 mg/ml while the sensitivity of Cs-NP's against all microorganisms under test started from a concentration of 20 mg/ml to 40 mg/ml except for the C.albicans species. Hematological activity was also tested in via measuring the RBCs, platelets count and clotting time against healthy, diabetic and hypercholesterolic blood samples. Measurement showed a decrease in RBCs and platelets count by adding Cs-NP’s or Cs-CuO-NP's to the three blood samples. Cs-NP’s success to decrease the clotting time for healthy and diabetic blood acting as a procoagulant agent, while adding biogenic CuO-NP’s to Cs-NP’s increased clotting time considering as an anticoagulant agent for hyperchloesterolic blood samples.

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Efficient biosynthesis of CuO nanoparticles with potential cytotoxic activity

Cited by 25 publications

References 53 publications

Photocatalysis and adsorption kinetics of azo dyes by nanoparticles of nickel oxide and copper oxide and their nanocomposite in an aqueous medium

Photocatalysis and adsorption kinetics of azo dyes by nanoparticles of nickel oxide and copper oxide and their nanocomposite in an aqueous medium

Integration of Cotton Fabrics with Biosynthesized CuO Nanoparticles for Bactericidal Activity in the Terms of Their Cytotoxicity Assessment

Investigation of the Antimicrobial Activity and Hematological Pattern of Nano-Chitosan and its Developed Nano-Copper Composite

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