Efficient and green one‐pot synthesis of Knoevenagel condensation catalyzed nano metal–organic frameworks in water

Abstract

Metal-organic frameworks (MOFs), Mlam-NH-66-UiO and EtA-NH-66-UiO, were prepared via post-synthesis of the H 2 N-66-UiO and used as an efficient heterogeneous catalyst for Knoevenagel condensation of various aldehydes with malononitrile in water. The modified MOFs exhibited excellent catalyst activities in heterogeneous phase because of their large pore sizes and surface area, porosity, and the number of catalytically active sites (-NH 2 ) on structures. In addition, the catalysts can be recycled and reused without decomposition of MOF structure and losing catalytic activity.

A new 2D coordination polymer as bifunctional heterogeneous catalyst for tandem deacetalization‐Knoevenagel reaction

“…α,β-unsaturated compounds can be prepared through Knoevenagel condensation reaction catalyzed by various materials such as metal-organic frameworks (MOFs), porous organic polymers, functionalized silica-based compounds, and magnetic nanoparticle-supported catalysts. [4][5][6][7] α,β-unsaturated nitriles are important chemicals for the preparation of pharmaceuticals and functional compounds, which can be synthesized via one-pot reactions. [8][9][10][11] Onepot tandem deacetalization-Knoevenagel reaction has been explored for the straightforward preparation of α,β-unsaturated nitriles.…”