We present the results of the study of long term orbital evolution of space debris objects, formed from end of life space vehicles (SV) of satellite radio navigation systems in the medium Earth orbit (MEO) region. Dynamical features of the evolution of objects in this region have been studied on the basis of 20 year laser surveillance with the Etalon 1 and Etalon 2 satellites and the results of numerical simulation of the long term evolution of operating and disposal orbits of uncontrolled GLONASS and GPS SVs. It is shown that perturbations from secular lunisolar resonances produce an eccentricity growth for orbits with inclina tions chosen for navigation constellations; this significantly changes the positions of these orbits in space and results in the ingress of end of life objects into the area of operating SVs.