Efficiency of fleece-bound sealing (TachoSil®) of air leaks in lung surgery: a prospective randomised trial☆

Anegg, Udo; Lindenmann, Jörg; Matzi, Veronika; Smolle, Josef; Maier, Andrea B.; Smolle‐Jüttner, Freyja Maria

doi:10.1016/j.ejcts.2006.11.033

Cited by 133 publications

(101 citation statements)

References 15 publications

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“…A recent study examined the use of same biodegradable spray polymer for the closure of IOAAL after minimally invasive pulmonary resection was not a randomised controlled trial (13). Other randomised controlled trials analysing lung sealant efficacy were almost exclusively in patients undergoing thoracotomy (14)(15)(16). Cost analysis showed a significant reduction of hospitalisation costs, although no significant differences in postoperative complications were showed.…”

Section: Discussionmentioning

confidence: 99%

Cost-effectiveness analysis of sealant impact in management of moderate intraoperative alveolar air leaks during video-assisted thoracoscopic surgery lobectomy: a multicentre randomised controlled trial

et al. 2017

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Section: Discussionmentioning

confidence: 99%

Cost-effectiveness analysis of sealant impact in management of moderate intraoperative alveolar air leaks during video-assisted thoracoscopic surgery lobectomy: a multicentre randomised controlled trial

et al. 2017

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“…It has found applications for several different surgical fields, including hemostasis and bile sealing in liver surgery and hemostasis in kidney tumor resection (5,6). Regarding general thoracic surgery, the use of TachoSil ® following pulmonary resection not only reduces the air leak volume, but also allows an early removal of chest drains and an early discharge (7). However, in the literature, there are few articles about the effectiveness of the use of fibrin sealant patch for reducing lymphatic leakage in thoracic surgery.…”

Section: Discussionmentioning

confidence: 99%

Chylothorax after mediastinal ganglioneuroma resection treated with fibrin sealant patch: a case report

et al. 2017

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Chylothorax is a severe condition resulting from the accumulation of chyle into the pleural space.We report the treatment of postoperative chylothorax after resection of mediastinal ganglioneuroma in a 17-year-old boy. Since conservative measures were not effective, we performed direct ligation of lymphatic vessels and pleurodesis. At subsequent surgical re-exploration for persisting chylothorax, accurate inspection of pleural cavity revealed residual chyle leakage. Fibrin sealant patches (TachoSil ® ) were placed over the source of leak with complete resolution of chylous effusion. To our knowledge, this is the first report of postoperative chylothorax successfully treated by the use of a fibrin sealant patch.

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“…It has a large patch of 9.5 cm x 4.8 cm x 0.5 cm, a medium patch of 4.8 cm x 4.8 cm x 0.5 cm and a small patch of 3.0 cm x 2.5 cm x 0.5 cm. At our Hospital, TachoSil is currently available for clinical practice and it is distributed by the hospital pharmacy and this product is currently approved in Europe for supportive haemostatic treatment in surgery, since the efficacy and safety of TachoSil was already demonstrated in many surgeries [17][18][19][20][21].…”

Section: Picturementioning

confidence: 99%

Post-Cesarean Section Hemorrage Treated by a Collagen Patch Coated with the Human Coagulation Factors

Tinelli¹

2011

J Clinic Case Reports

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Uterine hemorrhage is a common problem at the time and after caesarean section especially in a repeat caesarean section, where the surgical techniques used widely differ. An inadequate hemostasis of the uterine incision and the vesical-uterine vessels during CS, in closed and open visceral peritoneum, could lead to early hemorrhagic compliances, to control by further surgery.We present the case of a 31 year old woman undergoing a scheduled repeat emergency caesarean section. She had progressive bleeding from the incision site during the first post-operative days, since in third day she developed a hemorrhagic shock for a hemoperitoneum. Patient was re-operated and bleeding at uterine site incision was not controlled by traditional management including intravenous oxytocin and ergometrine, intramyometrial ergometrin and local hemostatic sutures, but was successfully controlled by equine collagen patch coated with human coagulation factors. Her post operative period was uneventful and she and her baby were discharged in good condition on day 5. Both of them were doing well on a follow up visit after 1 month.

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Efficiency of fleece-bound sealing (TachoSil®) of air leaks in lung surgery: a prospective randomised trial☆

Abstract: The use of TachoSil following pulmonary resection resulted in a reduction in air leakage compared with standard techniques. This reduction in air leakage resulted in a significant reduction in both the time to chest drain removal and the period of hospitalisation.

Cited by 133 publications

References 15 publications

Cost-effectiveness analysis of sealant impact in management of moderate intraoperative alveolar air leaks during video-assisted thoracoscopic surgery lobectomy: a multicentre randomised controlled trial

Cost-effectiveness analysis of sealant impact in management of moderate intraoperative alveolar air leaks during video-assisted thoracoscopic surgery lobectomy: a multicentre randomised controlled trial

Chylothorax after mediastinal ganglioneuroma resection treated with fibrin sealant patch: a case report

Post-Cesarean Section Hemorrage Treated by a Collagen Patch Coated with the Human Coagulation Factors

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