Efficiency and safety of using protein sparing modified fast in pediatric and adolescent obesity treatment

Caroli, M.; Chiarappa, S.; Borrelli, Renato; Martinelli, Rosanna

doi:10.1016/s0271-5317(05)80531-7

Cited by 8 publications

(12 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most studies were published in the 1990s (n = 13), seven in the 1980s and four since 2000. Most were conducted in the United States (n = 13), with the remaining conducted in either Austria (n = 6), Italy (n = 4), or Australia (n = 1) . Most were pre‐post studies (n = 16), with other study types including four nonrandomized comparison studies, two randomized controlled trials, and two chart reviews …”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Efficacy of very low‐energy diet programs for weight loss: A systematic review with meta‐analysis of intervention studies in children and adolescents with obesity

et al. 2019

View full text Add to dashboard Cite

The objective of this review was to evaluate the efficacy and safety of very low-energy diet (VLED) programs for weight loss in children and adolescents with obesity. Six electronic databases were searched identifying 24 eligible studies (16 pre-post studies, four nonrandomized trials, two randomized controlled trials [RCTs], and two chart reviews) published up to October 2018. Studies were in English, implemented a VLED (≤3360 kJF/day [≤800 kcal/day] or <50% estimated energy requirements) in 5-to 18-year-olds with obesity, and reported at least one weight-related outcome. Weight-related outcomes significantly improved postintervention in all studies. Meta-analysis of 20 studies indicated a mean 10.1 kg (95% confidence interval [CI], 8.7-11.4 kg, P < 0.001; I 2 = 92.3%) weight loss following interventions lasting 3 to 20 weeks. Moderator analysis indicated greater weight loss in adolescent-only studies (10-18 years) and formulated meal replacement interventions and inpatient settings. Meta-analysis of seven studies reporting weight at follow-up (5-14.5 months from baseline) indicated 5.3 kg mean weight loss (CI, 2.5-8.0 kg, P < 0.001; I 2 = 50.6%). Details of adverse events were limited. VLED programs are effective for treating children and adolescents with obesity. However, conclusions on their safety cannot be drawn from the existing literature at this time. Future studies should include long-term follow-up with ongoing support and comprehensive monitoring of all adverse events.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Six studies had less than 10 participants . Seven of the interventions incorporated an inpatient phase of at least 1 week, 15 were outpatient based, and two did not describe the intervention setting …”

Section: Resultsmentioning

confidence: 99%

Efficacy of very low‐energy diet programs for weight loss: A systematic review with meta‐analysis of intervention studies in children and adolescents with obesity

et al. 2019

View full text Add to dashboard Cite

show abstract

“…In examining these 45 programmes, some studies did not describe how participants were recruited (143,223,317–320), while others were recruited from physician's offices (207,321) or were volunteers (144). In all of these studies there was no randomization of subjects to either intervention or control groups increasing the potential for selection bias.…”

Section: Synthesis Of Findings – Results and Discussionmentioning

confidence: 99%

Reducing obesity and related chronic disease risk in children and youth: a synthesis of evidence with ‘best practice’ recommendations

Flynn

McNeil

Maloff³

et al. 2005

Obesity Reviews

752

611

View full text Add to dashboard Cite

SummaryChildhood obesity is a global epidemic and rising trends in overweight and obesity are apparent in both developed and developing countries. Available estimates for the period between the 1980s and 1990s show the prevalence of overweight and obesity in children increased by a magnitude of two to five times in developed countries (e.g. from 11% to over 30% in boys in Canada), and up to almost four times in developing countries (e.g. from 4% to 14% in Brazil). The goal of this synthesis research study was to develop best practice recommendations based on a systematic approach to finding, selecting and critically appraising programmes addressing prevention and treatment of childhood obesity and related risk of chronic diseases.An international panel of experts in areas of relevance to obesity provided guidance for the study. This synthesis research encompassed a comprehensive search of medical/academic and grey literature and the Internet covering the years 1982-2003. The appraisal approach developed to identify best practice was unique, in that it considered not only methodological rigour, but also population health, immigrant health and programme development/evaluation perspectives in the assessment. Scores were generated based on pre-determined criteria with programmes scoring in the top tertile of the scoring range in any one of the four appraisal categories included for further examination. The synthesis process included identification of gaps and an analysis and summary of programme development and programme effectiveness to enable conclusions to be drawn and recommendations to be made.The results from the library database searches (13 158 hits), the Internet search and key informant surveys were reduced to a review of 982 reports of which 500 were selected for critical appraisal. In total 158 articles, representing 147 programmes, were included for further analysis. The majority of reports were included based on high appraisal scores in programme development and evaluation with limited numbers eligible based on scores in other categories of appraisal. While no single programme emerged as a model of best practice, synthesis of included programmes provided rich information on elements that represent innovative rather than best practice under particular circumstances that are dynamic (changing according to population subgroups, age, ethnicity, setting, leadership, etc.). Thus the findings of this synthesis review identifies areas for action, opportunities for programme development and research priorities to inform the development of best practice recommendations that will reduce obesity and chronic disease risk in children and youth.A lack of programming to address the particular needs of subgroups of children and youth emerged in this review. Although immigrants new to developed countries may be more vulnerable to the obesogenic environment, no programmes were identified that specifically targeted their potentially specialized needs (e.g. different food supply in a new country). Children 0-6 years of ag...

show abstract

“…Caroli et al . demonstrated significant reductions in the percentage‐estimated overweight after 8 weeks, in both prepubertal children and adolescents, with no negative impact on growth in the younger group 77 and significant reductions in %overweight, P = 0.0001 and increases in lean body mass, P = 0.0001 78 . Willi et al .…”

Section: Dietary Interventionsmentioning

confidence: 95%

“…Protein sparing modified fasts were used by five research groups in seven studies, all Non-RCTs. Caroli et al demonstrated significant reductions in the percentage-estimated overweight after 8 weeks, in both prepubertal children and adolescents, with no negative impact on growth in the younger group 77 and significant reductions in %overweight, P = 0.0001 and increases in lean body mass, P = 0.0001. 78 Willi et al also found a significant reduction in BMI during 8 weeks of PSMF in adolescents, P = 0.01 79 with a significant reduction in %IBW observed at 1-year follow up in 7-to 17-year-olds, P < 0.001.…”

Section: Dietary Prescriptionsmentioning

confidence: 96%

Systematic review of interventions in the management of overweight and obese children which include a dietary component

Collins¹,

Warren

Neve

et al. 2007

International Journal of Evidence-Based Healthcare

View full text Add to dashboard Cite

Background The prevalence of overweight and obesity in children and adolescents is increasing at an alarming rate around the world and prevention has become a key public health objective. Treatment and management of those already overweight and obese must be aligned with the best available evidence on effectiveness, if the risk of obesity-related morbidity and mortality is yet be reduced. Diet plays a pivotal role in successful treatment of obesity but to date, there is limited evidence on which to base practice. Objectives To identify and present the best available evidence on the optimal dietetic treatment and management of children and adolescent who are overweight or obese. Search strategy Published English language literature was searched using the electronic databases CINAHL, MEDLINE, PRE-MEDLINE, DARE, COCHRANE, EMBASE, AUSTROM, Current Concepts and Dissertation Abstracts. The databases were limited to English Language from 1975 until 2003. Government reports from the UK, USA and Australian were also searched and a hand search performed for the Journal of the Dietitians Association of Australia, International Journal of Obesity and the Journal of Human Nutrition and Dietetics and the bibliographies of retrieved articles. Selection criteria (i) Interventions that evaluated the effectiveness of nutrition or dietary interventions to treat or manage overweight and obesity; (ii) Children aged less than 18 years; and (iii) Participants were defined as overweight or obese by relative weight or a measure of body weight status, studies that reported body weight per se were excluded. Data collection and analysis An experienced professional librarian searched the databases, and two trained research assistants independently identified studies for retrieval and assessed each article for inclusion. The included studies were critically appraised for methodological quality by two people independently. Data were extracted from the appropriate articles and when a discrepancy arose, a third party would arbitrate. Main results There were 116 articles that met the inclusion criteria. While 49 articles described randomised controlled trials, they arose from 37 separate studies. There were 67 non-randomised trials. Meta-analyses were performed on eight studies that included both a dietary intervention component and an adequate control group and on four studies that had follow-up data. There was a high degree of heterogeneity between studies and this made comparisons between studies problematic. Interventions that include diet therapy generally result in significant weight loss, at least in the short term. Many studies were poorly designed and had no or only minimal follow up. The details of the dietary intervention were often inadequately described and dietary outcomes rarely reported, making repetition of the studies difficult. Reviewers' conclusions There is an urgent need for high quality studies investigating the optimal dietary approach to management of paediatric overweight and obesity. These studies require adequat...

show abstract

Efficiency and safety of using protein sparing modified fast in pediatric and adolescent obesity treatment

Cited by 8 publications

References 21 publications

Efficacy of very low‐energy diet programs for weight loss: A systematic review with meta‐analysis of intervention studies in children and adolescents with obesity

Efficacy of very low‐energy diet programs for weight loss: A systematic review with meta‐analysis of intervention studies in children and adolescents with obesity

Reducing obesity and related chronic disease risk in children and youth: a synthesis of evidence with ‘best practice’ recommendations

Systematic review of interventions in the management of overweight and obese children which include a dietary component

Contact Info

Product

Resources

About