Efficiency and pregnancy outcome of serial intrauterine device–guided hysteroscopic adhesiolysis of intrauterine synechiae

Prevention of intrauterine post-surgical adhesions in hysteroscopy. A systematic review

“…We identified 3 studies that specifically focused on the importance of an early hysteroscopy after hysteroscopic surgery for the prevention of post-operative IUA [22][23][24]. Precisely, two papers refer to IUA prevention after hysteroscopic adhesiolysis procedure (secondary prevention) [22,23] and the third one to the primary IUA prevention [24].…”

“…Precisely, two papers refer to IUA prevention after hysteroscopic adhesiolysis procedure (secondary prevention) [22,23] and the third one to the primary IUA prevention [24].…”

“…Pabuccu et al [23] compared two different approaches in preventing IUA formation after hysteroscopic adhesiolysis, in 71 women were randomized into 2 groups. Group 1 (n = 36) had an intrauterine device (IUD) inserted during hysteroscopic adhesiolysis, an early second-look office hysteroscopy 1 week later (with further IUA lysis) and, afterwards, 2 months of estrogen and progestin (medroxyprogesterone acetate) therapy (with removal of the IUD at the end of this period).…”

Influence of auto-cross-linked hyaluronic acid gel on pregnancy rate and hysteroscopic outcomes following surgical removal of intra-uterine adhesions

“…Although good anatomical results and pregnancy rates have been reported, there have been no randomized control trials to date to confirm the usefulness of such devices. Moreover, such devices expose patients to the potential risk of perforation and infection [21][22][23][24]. To avoid leaving foreign objects in the uterus and associated complications, novel approaches using biological biodegradable anti-adhesion barriers such as ACP gel (Hyalobarrier) and Oxiplex/AP gel (Intercoat) have been developed.…”

Competing Endoscopic Surgeries in the Era of Assisted Reproductive Technologies: Evidence and Practice

“…Management of moderate to severe disease may be a challenge, and repeated surgery may be necessary in some cases and may not always produce the desired outcome. 51,52 A prospective study evaluated 24 women with infertility (12 of whom had previously delivered) and 12 women with a history of recurrent abortions. Of these 24 women, 48% conceived after hysteroscopic adhesiolysis.…”