Efficacy of various intracanal medicaments against aerobic and facultative anaerobic microorganism found in human primary teeth with necrotic pulp: A randomized clinical trial

Paikkatt, Jophie V; Aslam, Sachin; Sechachalam, Sreedharan; Philomina, Beena; Kannan, V P; Madhu, S

doi:10.4103/jisppd.jisppd_152_17

Cited by 6 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[24] Studies have shown that chlorhexidine alone, although it has substantivity, is not a good microbial barrier. [25] A clinical study evaluating the antimicrobial effectiveness of medication with 1% CHX gel for 2 weeks found 1% CHX gel ineffective in completely eliminating aerobic and facultative anaerobic microorganisms. [25] However, another study found that medication with 1% CHX gel for a week caused a considerable amount of microbial load reduction (82.17% reduction in colony-forming units).…”

Section: Discussionmentioning

confidence: 99%

“…[25] A clinical study evaluating the antimicrobial effectiveness of medication with 1% CHX gel for 2 weeks found 1% CHX gel ineffective in completely eliminating aerobic and facultative anaerobic microorganisms. [25] However, another study found that medication with 1% CHX gel for a week caused a considerable amount of microbial load reduction (82.17% reduction in colony-forming units). [26] Due to these conflicting results, the present study evaluated CHX's antibacterial effectiveness with a highly sensitive molecular method and it was found that the total bacteria copy number in the canals after 1 week of medication with 2% CHX gel F I G U R E 3 Evaluation of the groups in terms of the number of S3 droplets.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Microbial analysis of endodontic infections in teeth with post‐treatment apical periodontitis before and after medication

Erşahan

Hepşenoğlu

2022

Aust Endodontic J

View full text Add to dashboard Cite

This study aimed to determine the intraradicular microbiota of previously root canal‐treated teeth with apical periodontitis and to investigate the antibacterial effectiveness of different intracanal medicaments. Sixteen patients with post‐treatment apical periodontitis were allocated into two groups according to the intracanal medicament used: calcium hydroxide (CH) and 2% chlorhexidine gluconate gel (CHX) group. Total bacterial loads, as well as the amount of Enterococcus faecalis (E. faecalis) were determined before (S1) and after (S2) chemomechanical preparation and finally, after intracanal medication (S3) by means of ddPCR. The unpaired t test was used to compare parametric. S3‐total bacteria copy number of the CH group was lower than the CHX group (p < 0.05). There was no statistical difference between the CHX‐ and the CH groups in terms of E.faecalis copy number (p > 0.05). But in terms of total bacteria, CH is better than CHX. Consequently, CH can be used to optimise the antibacterial efficiency of chemomechanical preparation in previously root canal‐treated teeth with apical periodontitis.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Microbial analysis of endodontic infections in teeth with post‐treatment apical periodontitis before and after medication

Erşahan

Hepşenoğlu

2022

Aust Endodontic J

View full text Add to dashboard Cite

show abstract

“…This in-vivo study aims to compare the antimicrobial activity of TAP and TAP with bromelain, a naturally available potent proteolytic, anti-inflammatory, and antibacterial extract derived from pineapples, against E. faecalis bacteria as an ICM. [20], with a 95% confidence interval (CI) and 80% statistical power, and the sample size per group was calculated to be 15 individuals. All participants involved in the study were duly informed about the experiment, and their written informed consent was obtained.…”

mentioning

confidence: 99%

Efficacy of Triple Antibiotic Paste and Bromelain Paste As Intracanal Medicament Against Enterococcus faecalis: An In-Vivo Study

Nikhade,

Agrawal,

Mahapatra

et al. 2023

Cureus

View full text Add to dashboard Cite

IntroductionMicroorganisms are pivotal contributors to pulp and periapical pathology, often culminating in endodontic treatment failures. The successful outcome of such treatment hinges on the effective eradication of microbial flora through various interventions, including intracanal medicaments (ICMs). However, Enterococcus faecalis (E. faecalis), a highly adaptive Gram-positive bacterium, exhibits remarkable resilience and can persist even after rigorous disinfection efforts. This study explores the efficacy of two ICMs, calcium hydroxide-based triple antibiotic paste (TAP) and a novel alternative containing bromelain, derived from pineapples, in combating E. faecalis infections in vivo.

show abstract

Evaluation of antibacterial efficacy of ultrasonic-activated and inactivated chlorhexidine (solution and gel) in infected root canals of primary anterior teeth

Kharsa

Laflouf

Albouni

et al. 2023

Pediatric Dental Journal

View full text Add to dashboard Cite

Efficacy of various intracanal medicaments against aerobic and facultative anaerobic microorganism found in human primary teeth with necrotic pulp: A randomized clinical trial

Cited by 6 publications

References 0 publications

Microbial analysis of endodontic infections in teeth with post‐treatment apical periodontitis before and after medication

Microbial analysis of endodontic infections in teeth with post‐treatment apical periodontitis before and after medication

Efficacy of Triple Antibiotic Paste and Bromelain Paste As Intracanal Medicament Against Enterococcus faecalis: An In-Vivo Study

Evaluation of antibacterial efficacy of ultrasonic-activated and inactivated chlorhexidine (solution and gel) in infected root canals of primary anterior teeth

Contact Info

Product

Resources

About