Efficacy of Triphala extracts on the changes of obese fecal microbiome and metabolome in the human gut model

Metabolomic profiling of health‐benefit compounds in fresh and preserved mustard greens

“…To prepare the system for sample analysis, 10 QC samples were run before the actual sample runs. Additionally, a QC sample was inserted into the analysis every 10 sample runs (Kwandee et al ., 2023; Tunsagool et al ., 2023).…”

“…To prepare the system for sample analysis, 10 QC samples were run before the actual sample runs. Additionally, a QC sample was inserted into the analysis every 10 sample runs(Kwandee et al, 2023;Tunsagool et al, 2023).For MS analysis, parameter settings from previous work(Wu et al, 2021) were utilised. In summary, both positive and negative ion modes of electrospray ionisation were employed, with a mass-to-charge ratio (m/z) range of 70-1050.…”

The synergistic ramification of insoluble dietary fiber and associated non-extractable polyphenols on gut microbial population escorting alleviation of lifestyle diseases

“… Significant changes in metabolite profile and tyrosine, phenyl alanine and tryptophan biosynthesis. ( Kwandee et al, 2023 ) Hawthorn (Crataegus pinnatifida) Procyanidin Not analysed In vivo administration Mice model Upragulate growth of Akkermansia, Bacteroides and Adlercreutzia, and decreased Lactobacillus, Bifidobacterium, Blautia, Lachnospiraceae and Subdoligranulum Reduced insulin resistance, oxidative stress ( Han et al, 2022 ) peanut skin Type A procyanidins Not tested In vivo administration Balb/c mice model Reverse the ulcerative colitis by improving gut barrier and modu;ating inflammatory cytokines Increase growth of Oscillibacter and Roseburia Decrease growth of Bacteroides , Helicobacter , Parabacteroides , Escherichia-Shigella , and Enterobacter ( Huang et al, 2022 ) Grape seed extract Proanthocyanidin polyphenol extract Not tested In vivo administration Mice model GSPE normalized the colonic Firmicutes/Bacteroidetes ratios, reversed the relative abundance of Weissella, Faecalibaculum, Bacteroides, Akkermansia and Ruminococcus 1 induced by HFD reduced HFD-induced insulin resistance and increased levels of adiponectin and leptin ( Du et al, 2021 ) Pomegranate juice Hydrolysable tannin Not mentioned In vivo fermentation Insulin resistance mice model Reduced glucose and lipid metabolic disorder, liver injury and insulin resistance; decreased the Firmicutes/Bacteroides ratio, reduced Coprococcus and Anaerotruncus, and increased Rikenellaceae and liver tumor necrosis factor-alpha and interleukin-1β levels, supressed liver IKKβ and NF-κB phosphorylation; and upragulated liver autophagy-related proteins LC3-II, P 62, and Beclin1. ( Cao et al, 2021 ) Quebracho wood extract Chestnut wood extract\ Tara pods extract profisetinidin condensed tannin hydrolysable ellagitannins hydrolysable gallotannins) Not tested In vitro digestion and fermentation Human gut microbiata Increase of genus Akkermansia , Lachnospiraceae and Ruminococcaceae sp.…”