Efficacy of Sphenopalatine Ganglion Radiofrequency in Refractory Chronic Cluster Headache

Salgado-López, Laura; Quintana-Schmidt, Cristian de; Nieto, Robert Belvis; Arnall, Carles Roig i; Rodríguez, R.; Holzapfel, María Jesús Álvarez; Molet-Teixidó, Joan

doi:10.1016/j.wneu.2018.10.007

Cited by 26 publications

(41 citation statements)

References 24 publications

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“…All patients with CCH had recurrence within 30 months after the PRF procedure. To some extent, this outcome conflicts with the current literature, in which the mean effectiveness period was reported to be 4.69 months after PRF. Moreover, 4 patients experienced a longer effectiveness period that varied from 73 to 151 months after PRF.…”

Section: Discussioncontrasting

confidence: 95%

“…In that study, 70.8% of the patients with CCH achieved PR, and 16.7% achieved absolute pain relief. Our efficacy outcomes for CCH are identical to those observed by Salgado‐López et al…”

Section: Discussionsupporting

confidence: 89%

“…Postganglionic parasympathetic fibers that originate from the SPG are associated with the formation of the orbital, palatine, nasal, and pharyngeal branches. PRF of the SPG may interdict the parasympathetic activation pathway, block the transmission of parasympathetic signals, and prevent CH attacks from initiating . When reversible neuromodulatory effects are weakened or parasympathetic activation is strengthened, CH recurrence may unavoidably occur.…”

Section: Discussionmentioning

confidence: 99%

“…Subsequently, studies have reported the efficacy of SPG‐PRF therapy for patients with CH. The available limited literature suggests that PRF of the SPG is a quick, effective, and safe approach for treating refractory CHs . In our previous study, we found that computerized tomography (CT)‐guided PRF of the SPG had an efficacy rate of 85% for treating ECHs.…”

Section: Introductionmentioning

confidence: 94%

“…Our previous study reported the outcomes of 13 patients with ECH and 3 with CCH who underwent PRF as an alternative treatment. However, the follow‐up periods in recent studies have been relatively short, except for a retrospective study conducted by Salgado‐López et al. Limited evidence of SPG‐PRF for ECHs was shown.…”

Section: Introductionmentioning

confidence: 99%

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Long‐term Outcomes of Computerized Tomography–Guided Sphenopalatine Ganglion–Targeted Pulsed Radiofrequency for Refractory Cluster Headache

et al. 2019

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Objective To further evaluate the efficacy and safety of computerized tomography–guided sphenopalatine ganglion–targeted pulsed radiofrequency treatment for patients with refractory episodic and chronic cluster headache (CH). Methods Forty‐five patients with refractory episodic CH and 14 patients with chronic CH who underwent computerized tomography–guided sphenopalatine ganglion–targeted pulsed radiofrequency between January 2011 and December 2018 at the Beijing Tiantan Hospital were included and analyzed in this retrospective cohort study. Results A total of 59 patients underwent 106 computerized tomography–guided pulsed radiofrequency procedures throughout the observational period. Effective remission was observed in 95.6% and 64.3% of patients with refractory episodic and chronic CH, respectively. Repeated computerized tomography–guided sphenopalatine ganglion–targeted pulsed radiofrequency procedures for recurrent CH was also proven to be effective. No severe side effects or complications were observed in this study. Conclusion The computerized tomography–guided sphenopalatine ganglion–targeted pulsed radiofrequency procedure is an effective, safe, and repeatedly effective strategy for refractory CH. For patients who have not responded to conservative treatment, this minimally invasive intervention is a reliable alternative.

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Section: Discussioncontrasting

confidence: 95%

“…In that study, 70.8% of the patients with CCH achieved PR, and 16.7% achieved absolute pain relief. Our efficacy outcomes for CCH are identical to those observed by Salgado‐López et al…”

Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

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