Efficacy of single dose intramuscular methylprednisolone injection into the masseter muscle following the surgical extraction of impacted lower third molars.

Abstract

Aim and Objectives: The clinical study was conducted to evaluate the effect of a single 40 mg dose of methylprednisolone into the masseter muscle via the intrabuccal approach following the surgical extraction of impacted lower third molars under local anesthesia.
 Materials and Methods: In this single center, prospective, randomized controlled, double blind study 100 participants were divided into 2 groups. The study group received a single dose of Inj Methylprednisolone 40mg into the masseter muscle via the intrabuccal approach postoperatively, while the control received an I.M placebo drug. The efficacy of this procedure in controlling typical post-operative complications (pain, swelling, and mouth opening) was evaluated.
 Results: The patients administered methylprednisolone showed superior results after 2 and 5 days in terms of facial swelling (p < 0.05) and on 5th day after intervention with a p-value of 0.008 in terms on pain.
 Conclusion: Results obtained showed that 40 mg of Methylprednisolone can effectively reduce the patient discomfort post operatively after surgical removal of impacted teeth.