Efficacy of Single Dose Azithromycin as Prophylactic Antibiotic in Surgical Removal of Mandibular Third Molars: A Clinical Study

Sane, Vikrant Dilip; Gadre, Kiran Shrikrishna; Chandan, Sanjay; Ramanojam, Shandilya; Singh, Vikram; Halli, Rajshekhar

doi:10.1007/s12663-012-0464-5

Cited by 2 publications

(2 citation statements)

References 14 publications

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“…Yet, they mentioned that amoxicillin should be rather used with clavulanic acid to lower the chance of dry socket [12]. In addition, azithromycin was mentioned to be effective when given 1 hour before third molar extraction surgery to prevent dry socket [13]. It has been also effective when given post-operatively with single dose of 500 mg per day for 3 days after extraction [14].…”

Section: *Heavy Smoker Is Considered If the Number Of Cigarettes Is G...mentioning

confidence: 99%

Dry Socket: An Infectious Process Treated by Ciprofloxacin: Case Studies

Khalil

2022

JAMMR

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Dry socket is considered as the most common complication following tooth extraction. The incidence of dry socket is around 3% for all routine extractions and might surpass 30% for impacted mandibular third molars. It is accompanied by a partially or totally disintegrated blood clot within the alveolar socket, with or without halitosis. Dry socket is mainly manifested by severe irradiating pain that starts 1 to 4 days after dental extraction where the socket becomes denuded, exposed and tender to touch. Based on findings following previous bacterial culture and antibiogram on alveolar swab of rebellion cases of dry socket, we proposed a new pathogenesis theory based on infectious process. Antibiogram showed sensitivity to ciprofloxacin. Based on this fact we proposed a new treatment that consists of prescribing ciprofloxacin to cases unresponsive to topical conventional treatment. In this paper, we present a serial of 6 cases of dry socket following simple and surgical extraction procedures which were mostly associated with previous infection. The onset of pain started after 1-4 days of extraction where it was radiating and nonresponsive to pain killers. Clinical examination revealed exposed denuded socket in all subjects. All 6 patients were ASA1 and none has allergy to ciprofloxacin where the later was prescribed at 500 mg 3 times per day for 5 days. All patients were totally relieved in 12 to 24 hours after antibiotic intake. This clinical result, in addition to previous laboratory findings, support more the infectious process in the pathogenesis of dry socket.

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Section: *Heavy Smoker Is Considered If the Number Of Cigarettes Is G...mentioning

confidence: 99%

Dry Socket: An Infectious Process Treated by Ciprofloxacin: Case Studies

Khalil

2022

JAMMR

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“…The most common procedure done by Oral and Maxillofacial Surgeons in the world is surgical extraction of impacted mandibular third molars under local anaesthesia on an outpatient basis 1,2. The usual postoperative sequelae following surgical extraction of mandibular third molars have been reported as pain, swelling, and trismus 3 . On occasions postoperative healing complications such as alveolar osteitis, surgical site infection, fever and lymphadenopathy may occur 4 .…”

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confidence: 99%

Evaluation of Adjunctive Low Level Laser Therapy in Postoperative Management of Pain, Swelling, Trismus Following Surgical Removal of Impacted Mandibular Third Molars

Manodh

2022

Int J Life Sci Pharm Res

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Our aim is to evaluate the effectiveness of Low Level Laser Therapy (LLLT) in the control of postoperative pain, swelling, and trismus associated with the surgical removal of impacted mandibular third molars. This study was carried out as a single centre, prospective study with a sample size of 30 patients to evaluate the effectiveness of LLLT following surgical removal of impacted third molars. Patients were randomly divided into two groups of 15 each. Group 1(Study /LLLT group) consisted of patients undergoing LLLT and with the use of postoperative analgesics and antibiotics. Group 2 (Control) included patients who were administered postoperative analgesics and antibiotics without the concurrent use of LLLT. The predictor variable was the LLLT application following mandibular third molar impaction surgery. The outcome variables namely pain, swelling, and trismus were evaluated on the day of surgery and 1st, 3rd, and 7th postoperative days (POD).Results:The pain was highest on POD 1 and gradually reduced by POD 7 in the study group when compared to the control group. Swelling showed a steep increase on POD 1 and thereafter a gradual reduction was observed on POD 7, when compared to the control group, the study group showed a significant decrease in swelling. Mouth opening was the lowest on POD1 and gradually increased by POD 7 in the study group than in the control group. Conclusion: The results of the study suggest that the application of LLLT to impacted mandibular third molar sockets helps eliminate/or reduce postoperative pain, swelling, and trismus.

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Efficacy of Single Dose Azithromycin as Prophylactic Antibiotic in Surgical Removal of Mandibular Third Molars: A Clinical Study

Abstract: Objective To evaluate the efficacy of single dose Azithromycin as prophylactic antibiotic in surgical removal of mandibular third molar.

Cited by 2 publications

References 14 publications

Dry Socket: An Infectious Process Treated by Ciprofloxacin: Case Studies

Dry Socket: An Infectious Process Treated by Ciprofloxacin: Case Studies

Evaluation of Adjunctive Low Level Laser Therapy in Postoperative Management of Pain, Swelling, Trismus Following Surgical Removal of Impacted Mandibular Third Molars

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