Efficacy of Seprafilm for reducing reoperative risk in pediatric surgical patients undergoing abdominal surgery

Adhesive small bowel obstruction in children: should we still operate?

“…An accumulating body of literature supporting the safety and efficacy of antiadhesive technologies has emerged [16,17] but currently lacks strong support in the pediatric literature. Identifying high-risk procedures for adhesionrelated morbidity is of great interest to surgeons who aim to develop the targeted use of these adjuncts.…”

The incidence and morbidity of adhesions after treatment of neonates with gastroschisis and omphalocele: a 30-year review

“…First, these neonates undergo extensive peritoneal manipulation for abdominal wall closure and often need repeated laparotomy or insertion of prosthetic mesh, which are key factors inducing adhesion formation. Second, new techniques for abdominal wall closure and modern antiadhesive products give promising results in adults but need to be validated in neonatal laparotomy with high risk of adhesion-related morbidity [19,20].…”

“…The component separation technique is a promising technique to primarily close the abdominal wall defect without tension and avoiding insertion of foreign material [30]. Recently, Inoue et al [20] reported a significant reduction in incidence and severity of postoperative adhesions and mean relaparotomy operation time with the use of hyaluronate-based barrier membrane in a series of 122 neonates, infants, and children.…”

Intérêt des produits antiadhérentiels en chirurgie gynécologique

“…Son efficacité en terme de réduction des adhérences est établie en chirurgie digestive, ayant fait l'objet de plusieurs études randomisées chez l'homme [41,[43][44][45].…”