Efficacy of Rasayana Avaleha as adjuvant to radiotherapy and chemotherapy in reducing adverse effects

Abstract

Cancer is the most dreadful disease affecting mankind. The available treatments such as chemotherapy and radiotherapy have cytotoxic effects, which are hazardous to the normal cells of the patient, causing many unnecessary effects. This further leads to complications of the therapy, impaired health, and deterioration of quality of life, resulting in mandatory stoppage of the treatment. In the present study, the efficacy of an Ayurvedic formulation, Rasayana Avaleha, has been evaluated as an adjuvant medication to modern radiotherapy and chemotherapy. A total of 36 cancer patients were registered in this trial and were divided into two groups, group A and group B. In group A, the patients were treated with radiotherapy and chemotherapy along with adjuvant Rasayana Avaleha (RT + CT + RA), while in group B only radiotherapy and chemotherapy (RT + CT) were given, as the control group. After assessing the results, it was observed that Rasayana Avaleha gave better results in controlling the adverse effect of chemotherapy and radiotherapy in comparison with the control group. Therefore, Rasayana Avaleha has proved to be an effective adjuvant therapy in protecting patients from the adverse effects of chemotherapy and radiotherapy.

Positive effects on hematological and biochemical imbalances in patients with metastatic breast cancer stage IV, of BP-C1, a new anticancer substance

“…These findings can be used to develop DSNs for human use. 20 Treatment of cancer patients with herbo-mineral and metallic Ayurvedic drugs has been reported to significantly reduce the toxic effects of chemotherapy on various symptoms, and to have improved QoL, 21 , 22 although no positive effects on hematological parameters could be demonstrated. Various herbal medicines have also been tested in cancer patients treated with chemotherapy, and these have been used to reduce chemotherapy-induced nausea and vomiting, to improve patients’ QoL and to allow their subsequent chemotherapy.…”

Integratives Management unter Einsatz von Ayurveda-Medizin bei einer Patientin mit fortgeschrittenem Malignen Müllerschen Mischtumor - ein Fallbericht

“…Ein weites Spektrum von gravierenden Nebenwirkungen reduziert dabei die Lebensqualität bedeutend. Auch hierbei kann die Ayurveda-Medizin eine wirkungsvolle Hilfestellung leisten [20,35,36,40,41]. Im vorliegenden Fall kam es zu keinem Zeitpunkt der Chemotherapiesequenz sowie der beiden Bestrahlungsserien zu einschränkenden gravierenden Nebenwirkungen.…”

Phytochemicals based chemopreventive and chemotherapeutic strategies and modern technologies to overcome limitations for better clinical applications

“…At early stages, chemotherapy plays a curative role; however, in advanced stages, it has a different position where it could be a palliative or neo-adjuvant modality in various cancers (Alvarado-Miranda et al, 2009;Johnson, Bryant, Miles, Hogberg, & Cornes, 2011;Robati, Holtz, & Dunton, 2008). In addition to conventional chemotherapeutic drugs, emerging novel small molecule inhibitors and targeted drugs have been suggested as a promising way to treat cancer, but severe side effects, high cost, and limited outcomes among patients pose a challenge to establish them as ideal treatment modalities (Özdelikara & Tan, 2017;Vyas, Thakar, Baghel, Sisodia, & Deole, 2010). Moreover, the personalized treatment approach also targets only a subset of a population, but clinical outcomes are still insignificant.…”