2012
DOI: 10.1111/j.1468-3083.2012.04519.x
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Efficacy of Psoralen UV‐A therapy vs. Narrowband UV‐B therapy in chronic plaque psoriasis: a systematic literature review

Abstract: PUVA and NB-UVB are both effective therapies in treatment of psoriasis. Our results suggest that compared with NB-UVB, PUVA tends to clear psoriasis more reliably, with fewer sessions, and provides with longer lasting clearance. However, the long-term safety of PUVA, especially its cutaneous carcinogenic risk, and the easier administration procedure often lead dermatologists to prefer NB-UVB as first line phototherapy treatment in plaque type psoriasis.

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Cited by 74 publications
(57 citation statements)
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“…21 The number of sessions to clear was lower for PUVA (17 sessions) than for NB-UV-B (approximately 25 sessions); these conclusions are in accordance with those of the Cochrane review. The median duration of remission was studied by Markham and colleagues 22 ; this study reported 288.5 days for NB-UV-B group, and 231 days for PUVA.…”
Section: Efficacy Duration Of Remissionsupporting
confidence: 87%
“…21 The number of sessions to clear was lower for PUVA (17 sessions) than for NB-UV-B (approximately 25 sessions); these conclusions are in accordance with those of the Cochrane review. The median duration of remission was studied by Markham and colleagues 22 ; this study reported 288.5 days for NB-UV-B group, and 231 days for PUVA.…”
Section: Efficacy Duration Of Remissionsupporting
confidence: 87%
“…Bu çalışmada, yanıt oranları, yanıt için gerekli seans sayısı ve remisyon süresi açısından PUVA daha üstün bulunmakla birlikte, aslında, psoriasiste dar bant UVB'nin optimal tedavi sıklığı haftada üçtür. Haftada üç seans dar bant UVB ile haftada iki seans PUVA'yı karşılaştıran çalışmaların büyük kısmında her iki tedavi yönteminin eşit etkinlikte olduğu saptanmıştır (44,103). Bu nedenle de, psoriasiste birinci basamak fototerapi yöntemi dar bant UVB olup, PUVA'nın birinci basamağa geçebileceği durumlar, yaygın ve kalın plak psoriasis ve dar bant UVB'ye yetersiz yanıttır (44).…”
Section: Psoriasiste Fototerapiunclassified
“…El uso combinado con retinoides y específicamente con acitetrin oral, mejora la respuesta y alarga el período libre de enfermedad tanto en PUVA (RE-PUVA) como en fototerapia B de banda angosta 98,101,102 .…”
unclassified