Efficacy of prophylactic ketamine in preventing postoperative shivering

Dal, Didem; Kose, A.; Honca, Mehtap; Akıncı, Seda Banu; Başgül, Elif; Aypar, Ülkü

doi:10.1093/bja/aei148

Cited by 117 publications

(120 citation statements)

References 12 publications

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“…E sexto, houve um relato pobre de efeitos adversos, o que não significa que eles não ocorreram. Dal e col. 72 compararam baixas doses de cetamina, meperidina e placebo para prevenir tremores. Foram estudados 90 pacientes com idade entre 18 e 65 anos, estado físico ASA I ou II, submetidos à anestesia geral por 60 a 180 minutos, divididos em três grupos de 30.…”

Section: Prevenção Farmacológica De Tremoresunclassified

“…And sixth, the report on side effects was poor, but it does not necessarily mean that they were not present. Dal et al 72 compared low doses of ketamine, meperidine, and placebo in the prophylaxis of tremors. Ninety patients, ages 18 to 65 years, physical status ASA I or II, who underwent general anesthesia for 60 to 180 minutes, were divided in 3 groups of 30 each.…”

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confidence: 99%

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Tremores intra e pós-operatório: prevenção e tratamento farmacológico

Albergaria

Lorentz²,

Lima³

2007

Rev. Bras. Anestesiol.

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RESUMOAlbergaria VF, Lorentz MN, Lima FAS -Tremores Intra e Pós-Operatório: Prevenção e Tratamento Farmacológico. JUSTIFICATIVA E OBJETIVOS:Os tremores podem ocorrer como um efeito adverso da intervenção cirúrgica e anestesia. A incidência de tremores pós-operatórios varia entre 6,3% e 66%. Pacientes jovens, sexo masculino, uso de agentes anestésicos halogenados e tempo prolongado de anestesia ou procedimento cirúrgico estão relacionados com tremores. Os tremores são involuntários e apresentam-se como atividade muscular oscilatória com finalidade de aumentar a produção de calor. Tremor pós-operatório é uma desagradável complicação que está relacionada com o aumento de morbidade. O tremor aumenta o metabolismo, resultando em um acréscimo de 200% a 500% no consumo de oxigênio. CONTEÚDO:Discute as causas, a prevenção e o tratamento dos tremores intra-e pós-operatório em pacientes adultos e pediátri-cos submetidos à intervenção cirúrgica sob anestesia geral ou do neuroeixo. CONCLUSÕES:Os tremores são, juntamente com náuseas e vô-mitos, causas de intenso desconforto na sala de recuperação pós-anestésica, além de potencialmente prejudiciais por gerarem aumento da demanda metabólica. Embora a presença de tremores não tenha sido diretamente relacionada com a morbidade cardía-ca, a prevenção tem se tornado tema de debate e de vários artigos científicos. A prevenção e o tratamento de tremores devem ser implementados. Pacientes com reserva cardiopulmorar limitada podem sofrer com acidose láctica, dessaturação venosa mista e hipoxemia.Unitermos: ANESTESIA: Geral, Locorregional; COMPLICAÇÕES: hipotermia, tremor; TREMOR: prevenção, tratamento. SUMMARYAlbergaria VF, Lorentz MN, Lima FAS -Intra-and Postoperative Tremors: Prevention and Pharmacological Treatment. BACKGROUND AND OBJECTIVES:Tremors can be an adverse effect of the surgical intervention and anesthesia. The incidence of postoperative tremors varies from 6.3% to 66%. Young age, male gender, the use of halogenated anesthetics, and prolonged anesthesia or surgical procedure are related with tremors. Tremors are involuntary and present as oscillating muscular activity aiming at increasing heat production. Postoperative tremors are a disagreeable complication related with increased morbidity. Tremors increase the metabolism, resulting in a 200% to 500% increase in oxygen consumption. CONTENTS:The objective of this paper was to discuss the causes, prevention, and treatment of intra-and postoperative tremors in adults and children undergoing general anesthesia or neuroaxis anesthesia for surgical interventions. CONCLUSIONS:Tremors, along with nausea and vomiting, cause severe discomfort in the recovery room, besides being highly prejudicial because they generate an increase in the metabolism. Although the presence of tremors has not been directly related with cardiac morbidity, its prevention has become the subject of discussion and several scientific reports. Prevention and treatment of tremors should be implemented. Patients with limited cardiovascular reserve could devel...

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Section: Prevenção Farmacológica De Tremoresunclassified

mentioning

confidence: 99%

Tremores intra e pós-operatório: prevenção e tratamento farmacológico

Albergaria

Lorentz²,

Lima³

2007

Rev. Bras. Anestesiol.

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“…monitoring. 5,6 www.jmscr.igmpublication. Different methods are used to control shivering during anesthesia, broadly grouped as pharmacological or non pharmacological.…”

Section: Introductionmentioning

confidence: 99%

“…Whereas non pharmacological methods use equipment to maintain temperature of the body are effective, but expensive and lack practicality. 6,7 In recent times, ketamine and dexmedetomidine are used to prevent shivering during anesthesia, with excellent results. Ketamine is a competitive NMDA receptor antagonist and plays a role in thermoregulation at various levels by modulating serotonergic and noradrenergic neurons in the locus ceruleus.…”

Section: Introductionmentioning

confidence: 99%

Dexmedetomidine Infusion Versus Intravenous Low-Dose Ketamine Injection In Preventing Intraoperative Shivering During Spinal Anesthesia: A Comparative Study

Reddy¹

2017

JMSCR

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“…Shivering is a potentially serious event, resulting in increased metabolic rate; oxygen consumption may increased by 200% -500% along with a linear increase in carbon dioxide (CO 2 ) production [4]; ventilation and cardiac output; and adverse postoperative outcomes, such as wound infection; increased surgical bleeding; and morbid cardiac events. It can cause arterial hypoxemia, lactic…”

Section: Introductionmentioning

confidence: 99%

Comparison of clonidine and tramadol for the control of shivering under spinal anaesthesia

Attal¹,

Chhaya²,

Singh³

et al. 2015

Int J of Biomed & Adv Res

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Objectives: This study aimed to evaluate the relative efficacy of intravenously administered clonidine and tramadol for control of intraoperative shivering following spinal anaesthesia. Materials and Methods: A prospective, randomized, clinical controlled study was conducted on 60 ASA grade-I &II patients of either sex, aged 18-40 years, scheduled for elective lower abdominal and lower limb surgeries, under spinal anaesthesia. Patients who developed post spinal intraoperative shivering of grades 3 or 4, lasting for minimum period of 2minutes were included in the study, and randomly allocated to one of the two groups, group C (n=30), received Inj. clonidine 50µg i.v., and group T (n=30), received Inj. tramadol 50mg i.v. when shivering was observed. Time taken for control of shivering, response rate, recurrence rate, and side effects were observed. Results: The response rate was significantly higher in tramadol group than clonidine group at 1min, 2mins, and 3mins and 5mins intervals and comparable in both groups at 15 mins. The average time taken for disappearance of shivering was higher in clonidine group i.e. 5.76 ± 0.88mins as against 3.16 ± 0.84mins in tramadol group (P=0.038). Patients with incomplete response and recurrence were more in clonidine group. Side effects like hypotension, bradycardia, sedation and dry mouth were observed in clonidine group patients, and nausea and vomiting in tramadol group, but were controllable. Conclusion: Tramadol is better as compared to clonidine for control of intraoperative shivering under spinal anaesthesia due to rapid onset, higher response rate, lesser recurrence, lesser sedation and lesser hemodynamic alterations.

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Efficacy of prophylactic ketamine in preventing postoperative shivering

Abstract: Prophylactic low-dose ketamine was found to be effective in preventing postoperative shivering.

Cited by 117 publications

References 12 publications

Tremores intra e pós-operatório: prevenção e tratamento farmacológico

Tremores intra e pós-operatório: prevenção e tratamento farmacológico

Dexmedetomidine Infusion Versus Intravenous Low-Dose Ketamine Injection In Preventing Intraoperative Shivering During Spinal Anesthesia: A Comparative Study

Comparison of clonidine and tramadol for the control of shivering under spinal anaesthesia

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