Efficacy of preoperative inhaled LAMA/LABA combinations in patients with lung cancer and untreated COPD

Mizuno, Yoshimasa; Shirahashi, Koyo; Yamamoto, Hirotaka; Matsumoto, Miho; Miyamoto, Yusaku; Komuro, Hiroyasu; Hagiwara, Kiyohiko; Doi, Kiyoshi; Iwata, Hiroji

doi:10.23736/s2724-5691.21.08717-7

Cited by 2 publications

(1 citation statement)

References 26 publications

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“…Adding inhaled budesonide to a regime of inhaled tiotropium and formoterol, along with smoking cessation and chest physiotherapy in newly diagnosed COPD patients undergoing lung cancer surgery significantly reduced the PPC rate after one week of therapy compared to patients who were on a regime of tiotropium and formoterol (11.1% vs. 42.9%, P=0.04) (97). Increasing the treatment duration does not improve outcomes when comparing treatment duration of less than or greater than two weeks (98). Ju et al also investigated the effect of perioperative nebulised budesonide on outcomes following lobectomy.…”

Section: Copdmentioning

confidence: 93%

Optimisation of the high-risk thoracic surgical patient: a narrative review

Ahmed-Issap¹,

Mahendran²,

Abah³

2023

Shanghai Chest

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Background and Objective: High-risk patient cohorts have significant rates of morbidity and mortality following thoracic surgery, these outcomes can be modulated with preoperative intervention. This review article examines the existing literature pertaining to specific high-risk groups of patients and the impact of preoperative optimisation.Methods: We performed literature searches using the PubMed and BMJ search engine for Englishlanguage articles published from 1966 to 2022. A separate literature search was performed for each individual topic area to identify existing evidence of optimisation and the magnitude of effect. Key recommendations were compiled for each topic area.

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Section: Copdmentioning

confidence: 93%