Efficacy of Preoperative and Intraoperative Skin and Nail Surgical Preparation of the Foot in Reducing Bacterial Load

Becerro-de-Bengoa-Vallejo, Ricardo; Iglesias, Marta Elena Losa; Alou, Luís; Fernández, David Sevillano; Prieto, J.

doi:10.1111/j.1524-4725.2010.01619.x

Cited by 8 publications

(4 citation statements)

References 28 publications

(75 reference statements)

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“…The lack of bactericidal efficacy we observed for CHG is consistent with research showing CHG's poor antiseptic performance in surgical preparation hand [ 18 ] and toenail scrubs. [ 24 , 25 , 30 ] However, Marchetti and colleagues found that hand-rubbed CHG (Hisbiscrub) was an effective antiseptic and met the EN 12791 standards.…”

Section: Discussionmentioning

confidence: 99%

“…Cotton-tipped swabs have been used for bacterial sampling on skin of the foot and ankle previously. [ 23 – 26 ]…”

Section: Methodsmentioning

confidence: 99%

“…The limits of detection in the nailfold and skin tests were 1.33 × 10 2 and 1 × 10 2 CFU/cm 2 , respectively. [ 24 – 26 ] The laboratory investigator was blinded to the antiseptic test products individual participants had received.…”

Section: Methodsmentioning

confidence: 99%

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Effectiveness of surgical hand antisepsis using chlorhexidine digluconate and parachlorometaxylenol hand scrub

Becerro-de-Bengoa-Vallejo¹,

Fernández²,

Alou

et al. 2018

Medicine

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Background:Chlorhexidine and parachlorometaxylenol (PCMX) are antiseptics recommended for surgical hand antisepsis. To our knowledge, PCMX has not been evaluated for bactericidal efficacy “in vivo.Methods:We conducted a randomized, double-blind, controlled crossover trial to compare the bacterial loads on fingertips and fingernails under laboratory conditions after use of antiseptic test products, including chlorhexidine digluconate 4%, PCMX 3%, and a reference solution of propan-1-ol 60% (P-1). We assessed bacterial load after a prewash with soft soap, immediately after application of an antiseptic, and 3 hours after application and wearing of sterile, powder-free gloves. Our procedures followed those specified by European Norm (EN) 12791 for evaluating surgical hand antiseptics and using cotton swab for fingertips and fingernails.Results:Chlorhexidine digluconate 4% and PCMX 3% did not decrease bacterial load on the hands. The bactericidal performances of chlorhexidine digluconate 4% and PCMX 3% did not differ significantly. Chlorhexidine digluconate 4% and PCMX 3% increased bacterial load on the fingertips after participants had worn gloves for 3 hours. Fingernails had greater bacterial loads than skin on the fingertips.Conclusions:Chlorhexidine digluconate 4% and PCMX 3% had similar bactericidal efficacy, but they failed to meet the EN 12791 efficacy standard. Fingernails should be a particular focus of antisepsis in preparation for surgery.The trial was registered at ClinicalTrials.gov (ID: NCT02500758).

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Section: Discussionmentioning

confidence: 99%

“…Cotton-tipped swabs have been used for bacterial sampling on skin of the foot and ankle previously. [ 23 – 26 ]…”

Section: Methodsmentioning

confidence: 99%

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Effectiveness of surgical hand antisepsis using chlorhexidine digluconate and parachlorometaxylenol hand scrub

Becerro-de-Bengoa-Vallejo¹,

Fernández²,

Alou

et al. 2018

Medicine

Self Cite

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“…Studies have shown that eradicating bacteria from the nail folds and web spaces of the foot is particularly difficult, with a positive aerobic bacterial culture rate remaining greater than 70% for specimens from feet treated with standardized preparation methods involving povidone–iodine 6,7 . While the use of an effective pre‐operative skin‐preparation method is an important step in limiting surgical wound contamination and preventing infection, we believe an intraoperative antiseptic scrub is also of additional importance, due to the recontamination after nail removal that often occurs 8 …”

mentioning

confidence: 97%