Efficacy of platelet rich plasma in bone regeneration after surgical removal of impacted bilateral mandibular third molars: pilot study

Abstract

Within the limits of the present study it can be concluded that usage of PRP expedites bone regeneration, and reduces postoperative complications.

Effect of autologous platelet concentrates for alveolar socket preservation: a systematic review

“…Of the potential candidates for inclusion (n = 14), eight were excluded because they used the extraction socket of impacted third molars. [32][33][34][35][36][37][38][39] The main reason for exclusion was the fact that osteotomy of the socket walls is routine for the extraction of third molars, which affects the pattern, extent, and time of healing.…”

“…Extraction of impacted mandibular third molars Sammartino et al 33 Gürbüzer et al 37 Gawande and Halli 32 Vivek and Sripathi Rao 34 Gürbüzer et al 38 Mozzati et al 39 Rutkowski et al 36 Célio-Mariano et al 35 Growth factors associated with autologous bone or others biomaterials Anitua 61 No control group Simon et al 15 favouring the use of PRP was found (P = 0.03). 13 The other study 30 One study 13 used a questionnaire in the first week after extraction to evaluate patient perceptions of pain, oral function, general activities, and other symptoms.…”

Autologous Platelet Rich Plasma After Third Molar Surgery: A Comparative Study

“…Periodontal healing after impacted third molar surgeries, ridge augmentation and sinus grafting with freeze-dried bone allograft in combination with PRP provide a viable therapeutic alternative for implant placements [3,[5][6][7][8].…”

“…This study was carried out to evaluate the efficacy of PRP on bone regeneration after surgical removal of mandibular third molars. The results were evaluated both clinically and radiographically [3,6,10].…”

The use of bioactive factors to enhance bone regeneration: A narrative review

“…Overall, RCTs and prospective controlled studies where PRP was compared to unassisted socket healing (negative control) tended to show greater bone volume and enhancement of bone healing, with improved bone quality and better patient‐related outcomes (Alissa, Esposito, Horner & Oliver, ; Antonello Gde, Torres do Couto, Giongo, Correa & Chagas Junior, ; Celio‐Mariano, Melo & Carneiro‐Avelino, ; Dutta, Singh, Passi & Patter, ; Gawande & Halli, ; Ogundipe, Ugboko & Owotade, ; Rutkowski, Johnson, Radio & Fennell, ; Vivek & Sripathi Rao, ) (Appendix S3). In particular, several studies reported significantly reduced pain scores and enhanced soft tissue healing up to 14 days post‐extraction (Dutta et al., ; Ogundipe et al., ; Vivek & Sripathi Rao, ) and that PRP placed in third molars’ extractions sockets positively influenced periodontal parameters on second molars (Sammartino, Tia, Marenzi, Lauro & D'Agostino, ).…”