Efficacy of Platelet-rich Fibrin in the Treatment and Rehabilitation of Patients with Peri-implant Mucositis

Abstract

Aim: To evaluate the effectiveness of injectable platelet-rich fibrin (i-PRF) in the complex treatment and rehabilitation of patients with peri-implant mucositis. Materials and Methods: Clinical examination and treatment of 23 patients with peri-implant mucositis were carried out. Patients of the main group (n=11) were injected with liquid platelets-rich fibrin. In patients of the control group (n=12) the treatment protocol involved local antibacterial and anti-inflammatory therapy. The assessment of peri-implant tissues condition was performed on the basis of visual inspection, generally accepted instrumental and X-ray examination and was based on the data of periodontal tests and indexes. Results: In 72.7% of patients after i-PRF usage, reduction of inflammation was observed on the 3rd day of treatment; on the 7th day the clinical status corresponded to the norm. At the same time, in the control group a decrease of inflammation signs was revealed only in 33.3% of patients on the 3rd day and in 66.7% on the 7th day; complete elimination of inflammation in all patients was registered on the 14th day of observation. In 12-month follow-up examination the positive dynamic of peri-implant mucositis treatment was maintained in 81.8% of patients of the main group and in 50.0% of patients of the control group. Conclusions: The use of i-PRF in the complex treatment of peri-implant mucositis contributes to the rapid elimination of inflammation signs and bleeding of the gums surround the implants, accelerates the soft tissues regeneration, shortens treatment times and provides long lasting stabilization of the process.