Efficacy of On-Site Specimen Adequacy Evaluation of Image-Guided Fine and Core Needle Biopsies

Azabdaftari, G.; Goldberg, S. Nahum; Wang, Helen H.

doi:10.1159/000324997

Cited by 15 publications

(10 citation statements)

References 13 publications

(20 reference statements)

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“…Lachman et al 26 Klapman et al 11 Azabdaftari et al 16 28 Redman et al 32 Ghofrani et al 20 Raab et al 31 Moberly et al 27 Ghofrani et al 20 squares, the RD estimate for each study; lines, 95% CIs; and diamonds, estimates for the subgroup and overall summary estimates. The diamonds are centered on the estimate and the width is equal to the 95% CI.…”

Section: Multiplementioning

confidence: 99%

The Influence of Rapid Onsite Evaluation on the Adequacy Rate of Fine-Needle Aspiration Cytology

Schmidt

Witt

Lopez-Calderon

et al. 2013

American Journal of Clinical Pathology

123

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Rapid onsite evaluation (ROSE) has the potential to improve the adequacy rates of fine-needle aspiration (FNA) cytology. Studies have obtained variable results on the influence of ROSE. We conducted a systematic review and meta-analysis of studies on the influence of ROSE on FNA adequacy. We synthesized evidence across all anatomic locations. We only included studies that contained a control arm and compared cohorts with ROSE against cohorts without ROSE at a single location. We screened 2,179 studies and identified 25 studies that met our inclusion criteria. On average, ROSE improves the adequacy rate by 12%, but there was considerable variability across studies. The adequacy rate with ROSE depends on the non-ROSE adequacy rate. Sixty-five percent of the variability in the adequacy rate with ROSE was found to occur because of differences in the adequacy rate without ROSE. Studies with high non-ROSE adequacy rates showed low improvement after ROSE was implemented. Studies must account for the effect of the non-ROSE adequacy rate to determine the effect of ROSE on FNA adequacy rates.

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Section: Multiplementioning

confidence: 99%

The Influence of Rapid Onsite Evaluation on the Adequacy Rate of Fine-Needle Aspiration Cytology

Schmidt

Witt

Lopez-Calderon

et al. 2013

American Journal of Clinical Pathology

123

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show abstract

“…4,15 Alternatively, FNA may be obtained for adequacy evaluation and core is obtained if FNA is nondiagnostic, indeterminate, or indicates more materials for ancillary studies. 6,[18][19][20]26 TIS by definition are smears made from core biopsy at the time of procedure, and thus cytotechnologists and cytopathologists frequently need to interpret TIS of core biopsies for specimen adequacy evaluation and immediate diagnosis, respectively. Consequently, cytopathologists need to be familiar with the TIS morphology, which is different from that of FNA.…”

Section: Discussionmentioning

confidence: 99%

Increase of core biopsies in visceral organs–experience at one institution

Gupta¹,

Wang²

2010

Diagnostic Cytopathology

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All targeted core biopsies in the surgical pathology file and all cytology specimens from liver, lung, kidney, and pancreas accessioned in 1997, 2002, and 2007 in the Pathology Department at the Beth Israel Deaconess Medical Center, Boston, were culled. Cytology specimen type [touch imprint smear (TIS) from core-only, fine-needle aspiration (FNA)-only, or both] was determined. Seven hundred and fifty-eight targeted core biopsies were identified from the years 1997 (162), 2002 (249), and 2007 (347). Eight hundred and seventy-eight cytology specimens from the years 1997 (127), 2002 (264), and 2007 (487) were included. The overall percentage of TIS-only of all cytology specimens increased from 5.5 to 31% in 10 years and most prominently in the liver (14% in 1997 to 87% in 2007). In spite of the increasing use of core biopsies, the volume of cytology specimens from these organs increased from 127 in 1997 to 487 in 2007.

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“…1,2 Up to one third of fine-needle aspirations are non-diagnostic without ROSE. 3,4 In addition to the beneficial effect in terms of specimen adequacy, there is also the opportunity for triaging specimens for ancillary studies, as well as providing a preliminary diagnosis to the clinician to enable further decision making. 5 It can be very time-consuming to have a cytopathologist on site and can increase the costs of ROSE, which is an important drawback for the more widespread use of the technique.…”

Section: Introductionmentioning

confidence: 99%

Telecytology for rapid assessment of cytological specimens

et al. 2011

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We investigated the feasibility of telecytology for rapid on-site evaluation (ROSE) of cytological specimens. During a six-month study, 385 consecutive adult patients underwent image-guided fine needle aspiration biopsies of the lung or transbronchial needle aspirations of mediastinal lymph nodes. Direct smears were immediately wet-fixed and a cytopathologist or a trained cytotechnologist evaluated specimen adequacy using a telecytology system. Specimens were reported as adequate or inadequate. A total of 238 specimens (62%) were diagnosed without rapid assessment. The percentage of non-representative samples in the group without rapid evaluation was 42%. In the group of 147 specimens (38%) which underwent rapid evaluation, 48 (33%) were reported as inadequate and 99 (67%) as adequate. Only 22% of final diagnoses were non-representative, including samples which were assessed as inadequate by rapid evaluation. In three patients of 32, where the obtained material was recognized as adequate, final diagnoses were non-representative. Rapid evaluation with the use of telecytology improves the diagnostic yield of guided fine-needle aspiration biopsies by decreasing the percentage of non-representative specimens.

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Efficacy of On-Site Specimen Adequacy Evaluation of Image-Guided Fine and Core Needle Biopsies

Cited by 15 publications

References 13 publications

The Influence of Rapid Onsite Evaluation on the Adequacy Rate of Fine-Needle Aspiration Cytology

The Influence of Rapid Onsite Evaluation on the Adequacy Rate of Fine-Needle Aspiration Cytology

Increase of core biopsies in visceral organs–experience at one institution

Telecytology for rapid assessment of cytological specimens

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