Efficacy of nasal corticosteroid in preventing regrowth after adenoidectomy

Yıldırım, Yavuz Selim; Şentürk, Erol; Eren, Sabri Baki; Doğan, Remzi; Tuğrul, Selahattin; Özturan, Orhan

doi:10.1016/j.anl.2016.02.001

Cited by 15 publications

(11 citation statements)

References 17 publications

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“…Considering the aforementioned evidence on residual OSA, some studies have explored the potential use of anti-inflammatory therapy following T&A. Overall, the use of these agents appears to be beneficial, although the studies have been remarkably small to date and, therefore, do not specifically allow for more robust recommendations regarding their use widely [80][81][82].…”

Section: Nasal Corticosteroids and Montelukastmentioning

confidence: 99%

Treatment of Obstructive Sleep Apnea in Children: Handling the Unknown with Precision

Gozal

Tan

Kheirandish‐Gozal

2020

JCM

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Treatment approaches to pediatric obstructive sleep apnea (OSA) have remarkably evolved over the last two decades. From an a priori assumption that surgical removal of enlarged upper airway lymphadenoid tissues (T&A) was curative in the vast majority of patients as the recommended first-line treatment for pediatric OSA, residual respiratory abnormalities are frequent. Children likely to manifest persistent OSA after T&A include those with severe OSA, obese or older children, those with concurrent asthma or allergic rhinitis, children with predisposing oropharyngeal or maxillomandibular factors, and patients with underlying medical conditions. Furthermore, selection anti-inflammatory therapy or orthodontic interventions may be preferable in milder cases. The treatment options for residual OSA after T&A encompass a large spectrum of approaches, which may be complementary, and clearly require multidisciplinary cooperation. Among these, continuous positive airway pressure (CPAP), combined anti-inflammatory agents, rapid maxillary expansion, and myofunctional therapy are all part of the armamentarium, albeit with currently low-grade evidence supporting their efficacy. In this context, there is urgent need for prospective evidence that will readily identify the correct candidate for a specific intervention, and thus enable some degree of scientifically based precision in the current one approach fits all model of pediatric OSA medical care.

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Section: Nasal Corticosteroids and Montelukastmentioning

confidence: 99%

Treatment of Obstructive Sleep Apnea in Children: Handling the Unknown with Precision

Gozal

Tan

Kheirandish‐Gozal

2020

JCM

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“…In addition to symptomatic improvement, intranasal corticosteroids have also been shown to decrease rates of surgery for adenoid hypertrophy [68]. Studies have also examined the effect of steroid nasal spray after adenoidectomy and found that administration significantly prevented regrowth and obstructive nasal symptoms if administered 3 weeks post-adenoidectomy [69]. However, these results have been controversial, as other studies have found that fluticasone is not effective in improving adenoid hypertrophy [70].…”

Section: Non-surgical Therapy For Adenoid Hypertrophymentioning

confidence: 99%

Adenoidectomy in Children: What Is the Evidence and What Is its Role?

Schüpper

Nation

Pransky

2018

Curr Otorhinolaryngol Rep

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Purpose of Review Review the current state of the adenoidectomy procedure in the pediatric population with up-to-date indications for surgery, operative techniques, adverse events, non-surgical management of adenoid hypertrophy, and future directions. Recent Findings Adenoidectomy is indicated in children for the treatment of sleep-disordered breathing, nasal airway obstruction, recurrent acute otitis media, and chronic rhinosinusitis. A new recommendation was released in 2016, not supporting adenoidectomy for a primary indication of otitis media in children under 4 years old, including those with prior tympanostomy tubes, unless a distinct indication exists such as nasal obstruction or chronic adenoiditis. Although adenotonsillectomy is the mainstay of treatment for obstructive sleep apnea (OSA), recent studies have identified that non-obese patients with moderate OSA and small tonsils have comparable benefits with adenoidectomy alone with less complications. While conventional approaches such as indirect mirror-assisted curette and suction coagulation are still utilized, direct transnasal endoscopeassisted removal of the adenoids has proven to be a safe technique, with good short-and long-term outcomes. Novel nonsurgical therapies including immunotherapy have been evaluated. Summary Adenoidectomy is a safe procedure in the pediatric population and leads to excellent outcomes. Adverse events are rare, and hospitalization is uncommon. Children with sleep disturbance from nasal airway obstruction, ear disease, or chronic rhinosinusitis are the best operative candidates for this procedure.

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“…There may be more than one of the previously mentioned mechanism or even all of them, but the link is undeniable. [28][29][30][31] The main positive effect of nasal mometasone was on the nasal symptoms. There was significant improvement in all nasal symptoms that were present at the beginning of the study.…”

Section: Resultsmentioning

confidence: 99%

“…Also, nasal steroids have been studied extensively in the short-term management, long term management, and preventing recurrence of adenoids after adenoidectomy. [28][29][30][31][32][33][34] Local nasal steroids are recommended in the managment of viral and bacterial rhinosinusitis when symptoms are mild to moderate according to the British guidelines (NICE) and American guidelines. 1,11,20 In summary, steroids improve nasal obstruction through improving the congestion associated with nasal allergy and downsizing the present adenoids.…”

Section: Resultsmentioning

confidence: 99%

Evaluation of intranasal mometasone furate in the treatment of children with otitis media with effusion

Galil¹,

Ahmed²,

Wahab³

2019

Egyptian Journal of Neck Surgery and Otorhinolaryngology

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Introduction:Otitis media with effusion (OME) is the most common cause of acquired hearing loss in children. Conventional medical therapy has been tried for OME including antibiotics, decongestants, antihistamines, local and systemic steroids. The results of these trials are quite controversial. Intranasal mometasone furate is a powerful anti-inflammatory that has been thought to benefit in the treatment of OME. Objective: To evaluate the possible role of mometasone furate in the treatment of children with OME. Patients and methods: Sixty children having OME with significant hearing loss were included in the study. They were divided into two groups (A & B) each composed of 30 children. Patients in group A were given intranasal mometasone furate 100mcg/day, 1 puff in each nostril for 6 weeks. Patients in group B were subjected to watchful waiting without any medication for the same period. Clinical and audiological follow up was done after 6 weeks. Results: The overall results showed that there is no significant difference in improvement of OME between the 2 groups. Conclusions: Administration of intranasal mometasone furate for children with OME is not superior to watchful waiting.

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Efficacy of nasal corticosteroid in preventing regrowth after adenoidectomy

Cited by 15 publications

References 17 publications

Treatment of Obstructive Sleep Apnea in Children: Handling the Unknown with Precision

Treatment of Obstructive Sleep Apnea in Children: Handling the Unknown with Precision

Adenoidectomy in Children: What Is the Evidence and What Is its Role?

Evaluation of intranasal mometasone furate in the treatment of children with otitis media with effusion

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