Efficacy of narrow-margin excision of well-demarcated primary facial basal cell carcinomas

Kimyai‐Asadi, Arash; Alam, Murad; Goldberg, Leonard Harry; Peterson, S. Ray; Silapunt, Sirunya; Jih, Ming H.

doi:10.1016/j.jaad.2005.03.038

Cited by 100 publications

(73 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…3,9,13,14,17 However, a recently published metaanalysis provides a basis for determining the ideal surgical margin. In the current literature, most resections use predetermined surgical margins, ranging from 1 to 10 mm.…”

Section: Discussionmentioning

confidence: 99%

Does Loupe Magnification Reduce the Gap Between the Macroscopic and Microscopic Border of a Basal Cell Carcinoma?

Hoefkens

Fabre

Küsters‐Vandevelde

2014

Annals of Plastic Surgery

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Does Loupe Magnification Reduce the Gap Between the Macroscopic and Microscopic Border of a Basal Cell Carcinoma?

Hoefkens

Fabre

Küsters‐Vandevelde

2014

Annals of Plastic Surgery

View full text Add to dashboard Cite

show abstract

“…First, MMS has the advantage of complete evaluation of all margins. Second, margin positive rate was reported to be about 20%, if tumors were excised with a narrow margin of 1~3 mm without checking free margin17,18. Third, in our study, only 8% of tumors below 1cm required more than one excision.…”

Section: Discussionmentioning

confidence: 46%

Subclinical Infiltration of Basal Cell Carcinoma in Asian Patients: Assessment after Mohs Micrographic Surgery

Seo

Son

et al. 2011

Ann Dermatol

View full text Add to dashboard Cite

BackgroundSeveral differences in basal cell carcinomas (BCCs) were found, according to the ethnic group; for example, pigmented BCCs was more common in Asian or Hispanic patients. However, there are few reports on the subclinical extension of the BCC in Asian patients.ObjectiveThe aim of this study was to evaluate the subclinical infiltration of the basal cell carcinoma in Asian patients.MethodsAll patients with BCC who visited the department of dermatology at Korea University Ansan Hospital were treated with Mohs micrographic surgery. In 81 patients, 83 tumors of BCC were completely eradicated by Mohs micrographic surgery (MMS) from April 2001 to August 2008, and were reviewed in this study. Information recorded included the total margin and the number of stages of Mohs micrographic surgery, anatomic location, tumor size, presence of pigmentation, clinical type, and pathological subtype. We divided the clinical types into nodular, ulcerated, and pigmented, and the pathological types into nodular, micronodular, morpheaform, and adenoid. The BCC was of pigmented type if pigmentation covered more than 25% of the tumor, regardless of whether pigmentation was distinct, or if there was apparent pigmentation that covered more than 10% of the tumor.ResultsThe nose and cheek were the most common sites requiring more than one stage of surgery. In tumors smaller than 1 cm, 91.7% required only one stage of excision, compared with 60.6% in tumors larger than 1 cm. More than two Mohs stages were required in 25% of non-ulcerated BCCs and in 46.2% of ulcerated BCCs. Sixty eight percent of pigmented BCCs required only one stage of Mohs micrographic surgery. In cases of non-pigmented BCCs, only 45% required one Mohs stage. More than one Mohs stage was required in 19.2% of non-aggressive BCCs and in 42.9% of aggressive BCCs.ConclusionSubclinical infiltration differed between the two groups according to the size of the BCC (1 cm threshold) and most of the BCCs were located in the head and neck area. Considering this result, indication for MMS can be extended for BCCs larger than 1 cm in Asian patients. Ulcerated BCCs required more Mohs stages than non-ulcerated BCCs. Pigmented BCCs might show lesser subclinical infiltration than non-pigmented BCCs. Aggressive pathological subtypes showed more subclinical infiltration than the non-aggressive types; however, after evaluation of the border that was excised with MMS, mixed histologic types were found to be more frequent than generally accepted. Therefore, we consider that, when planning surgery, dermatologists should not place too much confidence in the pathologic subtypes identified by biopsy.

show abstract

“…The accepted predetermined margins of 3 mm for a small (i.e. <2 cm) well-defined lesion will offer an 85% cure rate (Wolf and Zitelli, 1987;Kimyai-Asadi et al, 2005). Morphoeic and larger BCCs require a greater excision margin; this is widely accepted as 5 mm.…”

Section: Surgical Managementmentioning

confidence: 99%

Textbook of Plastic and Reconstructive Surgery

Butler¹,

Ghali²,

Kalaskar³

2016

View full text Add to dashboard Cite

A CIP catalogue record for this book is available from The British Library.This book is published under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International license (CC BY-NC-ND 4.0). This license allows you to share, copy, distribute and transmit the work for personal and non-commercial use providing author and publisher attribution is clearly stated. Further details about CC BY licenses are available at http://creativecommons.org/ licenses/by/4.0The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. The user is advised to always check the product information and clinical procedures with the most up-to-date published product information and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or misuse or misapplication of material in this work.ISBN: 978-1-910634-37-0 (Hbk.) ISBN: 978-1-910634-38-7 (Pbk.) ISBN: 978-1-910634-39-4 (PDF) ISBN: 978-1-910634-40-0 (epub) ISBN: 978-1-910634-41-7 (mobi)

show abstract

Efficacy of narrow-margin excision of well-demarcated primary facial basal cell carcinomas

Cited by 100 publications

References 16 publications

Does Loupe Magnification Reduce the Gap Between the Macroscopic and Microscopic Border of a Basal Cell Carcinoma?

Does Loupe Magnification Reduce the Gap Between the Macroscopic and Microscopic Border of a Basal Cell Carcinoma?

Subclinical Infiltration of Basal Cell Carcinoma in Asian Patients: Assessment after Mohs Micrographic Surgery

Textbook of Plastic and Reconstructive Surgery

Contact Info

Product

Resources

About