Abstract:In this study, we evaluated the efficacy of NAC in dyspepsia symptoms in Helicobacter pylori (H. pylori) negative dyspeptic patients. Materials and Methods: In this randomized clinical trial, 85 patients with functional dyspepsia without H. pylori infection underwent treatment with a proton pump inhibitor (PPI) pantoprazole 40mg daily (n=41) with or without NAC 600mg twice a day (n=44) for 8 weeks. Patients' clinical symptoms and change in the severity of dyspepsia symptoms were compared between the groups. Re… Show more
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